Plasmodium falciparum eukaryotic translation initiation factor 3 is stabilized by quinazoline-quinoline bisubstrate inhibitors
Malaria drug resistance is hampering the fight against the deadliest parasitic disease affecting over 200 million people worldwide. We recently developed quinoline-quinazoline-based inhibitors (as compound 70) as promising new antimalarials. Here, we aimed to investigate their mode of action by usin...
Main Authors: | Dobrescu, Irina, Hammam, Elie, Dziekan, Jerzy Michal, Claës, Aurélie, Halby, Ludovic, Preiser, Peter, Bozdech, Zbynek, Arimondo, Paola B., Scherf, Artur, Nardella, Flore |
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Other Authors: | School of Biological Sciences |
Format: | Journal Article |
Language: | English |
Published: |
2024
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/174270 |
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