Enhancer infestation drives tumorigenic activation of inactive B compartment in Epstein-Barr virus-positive nasopharyngeal carcinoma

Enhancer infestation drives tumorigenic activation of inactive B compartment in Epstein-Barr virus-positive nasopharyngeal carcinoma

Nasopharyngeal carcinoma (NPC) is an Epstein-Barr virus (EBV)-associated malignant epithelial tumor endemic to Southern China and Southeast Asia. While previous studies have revealed a low frequency of gene mutations in NPC, its epigenomic aberrations are not fully elucidated apart from DNA hypermet...

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Bibliographic Details
Main Authors: Mizokami, Harue, Okabe, Atsushi, Choudhary, Ruchi, Mima, Masato, Saeda, Kenta, Fukuyo, Masaki, Rahmutulla, Bahityar, Seki, Motoaki, Goh, Boon-Cher, Kondo, Satoru, Dochi, Hirotomo, Moriyama-Kita, Makiko, Misawa, Kiyoshi, Hanazawa, Toyoyuki, Tan, Patrick, Yoshizaki, Tomokazu, Fullwood, Melissa Jane, Kaneda, Atsushi
Other Authors: School of Biological Sciences
Format: Journal Article
Language:English
Published: 2024
Subjects:
Medicine, Health and Life Sciences
Epstein-Barr virus
Nasopharyngeal carcinoma
Enhancer infestation
Online Access:https://hdl.handle.net/10356/174488

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