Utilizing molecular docking and cell validation to explore the potential mechanisms of lupenone attenuating the inflammatory response via NF-κB pathway

Utilizing molecular docking and cell validation to explore the potential mechanisms of lupenone attenuating the inflammatory response via NF-κB pathway

Diabetic nephropathy (DN), a common microvascular complicating disease of diabetes. Lupenone, a pentacyclic triterpenoid, has anti-inflammatory effects and can prevent type 2 diabetes mellitus and treat renal damage, however, the effects and mechanisms of lupenone in DN remain unclear. Thereby,the M...

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Bibliographic Details
Main Authors: Wang, Xiangpei, Liu, Mei, Li, Xiaofen, Zhang, Mei, Xu, Feng, Liu, Hongyun, Wu, Hongmei
Other Authors: School of Physical and Mathematical Sciences
Format: Journal Article
Language:English
Published: 2024
Subjects:
Medicine, Health and Life Sciences
Antiinflammatory agent
Cytokine
Online Access:https://hdl.handle.net/10356/174953

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