Silicon-containing thiol-specific bioconjugating reagent
A new bioconjugation reagent containing silicon has been developed for the selective reaction with thiols. The inclusion of silicon significantly improves chemoselectivity and suppresses retro processes, thereby exceeding the capabilities of traditional reagents. The method is versatile and compatib...
Main Authors: | Zhang, Zhenguo, Li, Lanyang, Xu, Hailun, Lee, Ken Chi-Lik, Jia, Zhenhua, Loh, Teck-Peng |
---|---|
Other Authors: | School of Chemistry, Chemical Engineering and Biotechnology |
Format: | Journal Article |
Language: | English |
Published: |
2024
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/178414 |
Similar Items
-
Thiol-specific silicon-containing conjugating reagent: β-silyl alkynyl carbonyl compounds
by: Teng, Shenghan, et al.
Published: (2023) -
Synthesis and Characterization of Quaternary Ammonium Salts Containing Carbonyl Functionality
by: Salim, Norazlinaliza
Published: (2007) -
Assembly of multicyclic isoquinoline scaffolds from pyridines : formal total synthesis of fredericamycin A
by: Wang, Fang-Xin, et al.
Published: (2022) -
A Transition Metal Carbonyl Probe for Use in a Highly Specific and Sensitive SERS-Based Assay for Glucose
by: Kong, Kien Voon, et al.
Published: (2016) -
Metal-free access to (spirocyclic) tetrahydro-β-carbolines in water using an ion-pair as a superacidic precatalyst
by: Zhang, Zhenguo, et al.
Published: (2022)