Yield enhancement and phase behaviors of cyclic peptide drug crystallization in the presence of polyethylene glycol additive
Crystallization of peptide drugs typically requires a lengthy period to attain reasonable yields due to slow crystallization kinetics of macromolecules. Herein we investigated the use of polyethylene glycol (8 kDa) (PEG 8k) as an additive to enhance the yield of salting-out crystallization of cyclic...
Main Authors: | Pu, Siyu, Hadinoto, Kunn |
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Other Authors: | School of Chemistry, Chemical Engineering and Biotechnology |
Format: | Journal Article |
Language: | English |
Published: |
2024
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Subjects: | |
Online Access: | https://hdl.handle.net/10356/179423 |
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