Yield enhancement and phase behaviors of cyclic peptide drug crystallization in the presence of polyethylene glycol additive

Crystallization of peptide drugs typically requires a lengthy period to attain reasonable yields due to slow crystallization kinetics of macromolecules. Herein we investigated the use of polyethylene glycol (8 kDa) (PEG 8k) as an additive to enhance the yield of salting-out crystallization of cyclic...

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Bibliographic Details
Main Authors: Pu, Siyu, Hadinoto, Kunn
Other Authors: School of Chemistry, Chemical Engineering and Biotechnology
Format: Journal Article
Language:English
Published: 2024
Subjects:
Online Access:https://hdl.handle.net/10356/179423

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