Fetal liver CD34+ contain human immune and endothelial progenitors and mediate solid tumor rejection in NOG mice

Fetal liver CD34+ contain human immune and endothelial progenitors and mediate solid tumor rejection in NOG mice

Background: Transplantation of CD34+ hematopoietic stem and progenitor cells (HSPC) into immunodeficient mice is an established method to generate humanized mice harbouring a human immune system. Different sources and methods for CD34+ isolation have been employed by various research groups, resulti...

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Bibliographic Details
Main Authors: Celhar, Teja, Li, Xinyi, Zhao, Yunqian, Tay, Hui Chien, Lee, Andrea, Liew, Hui Hua, Shepherdson, Edwin Kunxiang, Rajarethinam, Ravisankar, Fan, Yiping, Mak, Anselm, Chan, Jerry Kok Yen, Singhal, Amit, Takahashi, Takeshi
Other Authors: Lee Kong Chian School of Medicine (LKCMedicine)
Format: Journal Article
Language:English
Published: 2024
Subjects:
Medicine, Health and Life Sciences
Humanized mice
Fetal liver CD34
Online Access:https://hdl.handle.net/10356/179603

Internet

https://hdl.handle.net/10356/179603

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