Function of ArhGAP12 in the assembly and regulation of epithelial tight junctions
In epithelia cells, tight junctions (TJ) form selective gates that control the paracellular diffusion of ions and solutes, and they act as a border between the apical and basolateral plasma-membrane domains. TJ formation and function are regulated by Rho-GTPases, whose activities are controlled by g...
Main Author: | |
---|---|
Other Authors: | |
Format: | Thesis-Doctor of Philosophy |
Language: | English |
Published: |
Nanyang Technological University
2024
|
Subjects: | |
Online Access: | https://hdl.handle.net/10356/179880 |