Function of ArhGAP12 in the assembly and regulation of epithelial tight junctions

In epithelia cells, tight junctions (TJ) form selective gates that control the paracellular diffusion of ions and solutes, and they act as a border between the apical and basolateral plasma-membrane domains. TJ formation and function are regulated by Rho-GTPases, whose activities are controlled by g...

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Bibliographic Details
Main Author: Tambrin, Hana Maldivita
Other Authors: Alexander Ludwig
Format: Thesis-Doctor of Philosophy
Language:English
Published: Nanyang Technological University 2024
Subjects:
Online Access:https://hdl.handle.net/10356/179880

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