Effects of the consumption of algal biomass versus protein concentrate on postprandial satiety and metabolism
Algae are promising sources of nutritious and sustainable protein, but little is known about their metabolic health impact and acceptability as meal ingredients. This acute, randomized, controlled, five-way crossover trial compared whole algal biomasses and their corresponding protein concentrates t...
| Main Authors: | , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2024
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| Online Access: | https://hdl.handle.net/10356/181337 |
| _version_ | 1826112065575583744 |
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| author | Wu, Jia Yee Tso, Rachel Yong, Yi Ning Lim, Susanna Poh Suan Wheeler, Thomas Nag, Arup Cheng, Lirong Talukder, Md. Mahabubur Rahman Huffman, Lee Quek, Siew Young Leow, Melvin Khee Shing Haldar, Sumanto |
| author2 | Lee Kong Chian School of Medicine (LKCMedicine) |
| author_facet | Lee Kong Chian School of Medicine (LKCMedicine) Wu, Jia Yee Tso, Rachel Yong, Yi Ning Lim, Susanna Poh Suan Wheeler, Thomas Nag, Arup Cheng, Lirong Talukder, Md. Mahabubur Rahman Huffman, Lee Quek, Siew Young Leow, Melvin Khee Shing Haldar, Sumanto |
| author_sort | Wu, Jia Yee |
| collection | NTU |
| description | Algae are promising sources of nutritious and sustainable protein, but little is known about their metabolic health impact and acceptability as meal ingredients. This acute, randomized, controlled, five-way crossover trial compared whole algal biomasses and their corresponding protein concentrates to soy protein concentrate in terms of palatability, appetite, satiety, and metabolic response. Nineteen healthy Chinese males (21–50 years, 18.5–25.0 kg/m2) consumed noodle meals supplemented with 10 g of nori biomass/protein concentrate (NB/NC), Chlorella vulgaris biomass/protein concentrate (CB/CC) or soy protein concentrate control (CON) in randomized order. At regular intervals, blood samples were collected to measure biochemical markers, while gastrointestinal tolerance, palatability, and appetite were assessed using questionnaires and visual analog scales (VAS). Results indicated that algae-enriched meals were well-tolerated and comparable to soy in both visual appeal and smell, with NB and CC outperforming soy in aftertaste (p < 0.05). There were no significant differences between treatments in glucose, insulin, C-peptide, appetite/satiety, plasma ghrelin, and GLP-1. However, exploratory analysis of serum triglycerides revealed significant time × treatment effects (p < 0.004) and differences in incremental area under the curve (iAUC0–120 p = 0.0249). Our findings reveal that algal biomasses and protein concentrates are as comparable to soy protein concentrate in palatability, satiety, and metabolic outcomes, highlighting their potential as practical, sustainable, and nutritious ingredients. |
| first_indexed | 2025-03-09T10:29:35Z |
| format | Journal Article |
| id | ntu-10356/181337 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2025-03-09T10:29:35Z |
| publishDate | 2024 |
| record_format | dspace |
| spelling | ntu-10356/1813372024-12-01T15:39:37Z Effects of the consumption of algal biomass versus protein concentrate on postprandial satiety and metabolism Wu, Jia Yee Tso, Rachel Yong, Yi Ning Lim, Susanna Poh Suan Wheeler, Thomas Nag, Arup Cheng, Lirong Talukder, Md. Mahabubur Rahman Huffman, Lee Quek, Siew Young Leow, Melvin Khee Shing Haldar, Sumanto Lee Kong Chian School of Medicine (LKCMedicine) Singapore Institute of Food and Biotechnology Innovation. A*STAR Tan Tock Seng Hospital Duke-NUS Medical School Medicine, Health and Life Sciences Algal protein concentrate Alternative protein Algae are promising sources of nutritious and sustainable protein, but little is known about their metabolic health impact and acceptability as meal ingredients. This acute, randomized, controlled, five-way crossover trial compared whole algal biomasses and their corresponding protein concentrates to soy protein concentrate in terms of palatability, appetite, satiety, and metabolic response. Nineteen healthy Chinese males (21–50 years, 18.5–25.0 kg/m2) consumed noodle meals supplemented with 10 g of nori biomass/protein concentrate (NB/NC), Chlorella vulgaris biomass/protein concentrate (CB/CC) or soy protein concentrate control (CON) in randomized order. At regular intervals, blood samples were collected to measure biochemical markers, while gastrointestinal tolerance, palatability, and appetite were assessed using questionnaires and visual analog scales (VAS). Results indicated that algae-enriched meals were well-tolerated and comparable to soy in both visual appeal and smell, with NB and CC outperforming soy in aftertaste (p < 0.05). There were no significant differences between treatments in glucose, insulin, C-peptide, appetite/satiety, plasma ghrelin, and GLP-1. However, exploratory analysis of serum triglycerides revealed significant time × treatment effects (p < 0.004) and differences in incremental area under the curve (iAUC0–120 p = 0.0249). Our findings reveal that algal biomasses and protein concentrates are as comparable to soy protein concentrate in palatability, satiety, and metabolic outcomes, highlighting their potential as practical, sustainable, and nutritious ingredients. Published version This project was funded by the Singapore-New Zealand Bilateral Program on Future Food Research (grant id: A20D3b0072) and Singapore Institute of Food and Biotechnology Innovation (SIFBI). 2024-11-26T01:16:02Z 2024-11-26T01:16:02Z 2024 Journal Article Wu, J. Y., Tso, R., Yong, Y. N., Lim, S. P. S., Wheeler, T., Nag, A., Cheng, L., Talukder, M. M. R., Huffman, L., Quek, S. Y., Leow, M. K. S. & Haldar, S. (2024). Effects of the consumption of algal biomass versus protein concentrate on postprandial satiety and metabolism. Future Foods, 10, 100436-. https://dx.doi.org/10.1016/j.fufo.2024.100436 2666-8335 https://hdl.handle.net/10356/181337 10.1016/j.fufo.2024.100436 2-s2.0-85201764248 10 100436 en A20D3b0072 Future Foods © 2024 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). application/pdf |
| spellingShingle | Medicine, Health and Life Sciences Algal protein concentrate Alternative protein Wu, Jia Yee Tso, Rachel Yong, Yi Ning Lim, Susanna Poh Suan Wheeler, Thomas Nag, Arup Cheng, Lirong Talukder, Md. Mahabubur Rahman Huffman, Lee Quek, Siew Young Leow, Melvin Khee Shing Haldar, Sumanto Effects of the consumption of algal biomass versus protein concentrate on postprandial satiety and metabolism |
| title | Effects of the consumption of algal biomass versus protein concentrate on postprandial satiety and metabolism |
| title_full | Effects of the consumption of algal biomass versus protein concentrate on postprandial satiety and metabolism |
| title_fullStr | Effects of the consumption of algal biomass versus protein concentrate on postprandial satiety and metabolism |
| title_full_unstemmed | Effects of the consumption of algal biomass versus protein concentrate on postprandial satiety and metabolism |
| title_short | Effects of the consumption of algal biomass versus protein concentrate on postprandial satiety and metabolism |
| title_sort | effects of the consumption of algal biomass versus protein concentrate on postprandial satiety and metabolism |
| topic | Medicine, Health and Life Sciences Algal protein concentrate Alternative protein |
| url | https://hdl.handle.net/10356/181337 |
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