Global challenges and microbial biofilms: identification of priority questions in biofilm research, innovation and policy
Priority question exercises are increasingly used to frame and set future research, innovation and development agendas. They can provide an important bridge between the discoveries, data and outputs generated by researchers, and the information required by policy makers and funders. Microbial biofil...
| Main Authors: | , , , , , , , , , , , , , , , , , , , |
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| Other Authors: | |
| Format: | Journal Article |
| Language: | English |
| Published: |
2024
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| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/181343 |
| _version_ | 1826110231160029184 |
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| author | Coenye, Tom Ahonen, Merja Anderson, Skip Cámara, Miguel Chundi, Parvathi Fields, Matthew Foidl, Ines Gnimpieba, Etienne Z. Griffin, Kristen Hinks, Jamie Loka, Anup R. Lushbough, Carol MacPhee, Cait Nater, Natasha Raval, Rasmita Slater-Jefferies, Jo Teo, Pauline Wilks, Sandra Yung, Maria Webb, Jeremy S. |
| author2 | Singapore Centre for Environmental Life Sciences and Engineering |
| author_facet | Singapore Centre for Environmental Life Sciences and Engineering Coenye, Tom Ahonen, Merja Anderson, Skip Cámara, Miguel Chundi, Parvathi Fields, Matthew Foidl, Ines Gnimpieba, Etienne Z. Griffin, Kristen Hinks, Jamie Loka, Anup R. Lushbough, Carol MacPhee, Cait Nater, Natasha Raval, Rasmita Slater-Jefferies, Jo Teo, Pauline Wilks, Sandra Yung, Maria Webb, Jeremy S. |
| author_sort | Coenye, Tom |
| collection | NTU |
| description | Priority question exercises are increasingly used to frame and set future research, innovation and development agendas. They can provide an important bridge between the discoveries, data and outputs generated by researchers, and the information required by policy makers and funders. Microbial biofilms present huge scientific, societal and economic opportunities and challenges. In order to identify key priorities that will help to advance the field, here we review questions from a pool submitted by the international biofilm research community and from practitioners working across industry, the environment and medicine. To avoid bias we used computational approaches to group questions and manage a voting and selection process. The outcome of the exercise is a set of 78 unique questions, categorized in six themes: (i) Biofilm control, disruption, prevention, management, treatment (13 questions); (ii) Resistance, persistence, tolerance, role of aggregation, immune interaction, relevance to infection (10 questions); (iii) Model systems, standards, regulatory, policy education, interdisciplinary approaches (15 questions); (iv) Polymicrobial, interactions, ecology, microbiome, phage (13 questions); (v) Clinical focus, chronic infection, detection, diagnostics (13 questions); and (vi) Matrix, lipids, capsule, metabolism, development, physiology, ecology, evolution environment, microbiome, community engineering (14 questions). The questions presented are intended to highlight opportunities, stimulate discussion and provide focus for researchers, funders and policy makers, informing future research, innovation and development strategy for biofilms and microbial communities. |
| first_indexed | 2025-03-09T10:00:26Z |
| format | Journal Article |
| id | ntu-10356/181343 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2025-03-09T10:00:26Z |
| publishDate | 2024 |
| record_format | dspace |
| spelling | ntu-10356/1813432024-11-28T15:30:25Z Global challenges and microbial biofilms: identification of priority questions in biofilm research, innovation and policy Coenye, Tom Ahonen, Merja Anderson, Skip Cámara, Miguel Chundi, Parvathi Fields, Matthew Foidl, Ines Gnimpieba, Etienne Z. Griffin, Kristen Hinks, Jamie Loka, Anup R. Lushbough, Carol MacPhee, Cait Nater, Natasha Raval, Rasmita Slater-Jefferies, Jo Teo, Pauline Wilks, Sandra Yung, Maria Webb, Jeremy S. Singapore Centre for Environmental Life Sciences and Engineering Engineering Microbial biofilms Global challenges Priority question exercises are increasingly used to frame and set future research, innovation and development agendas. They can provide an important bridge between the discoveries, data and outputs generated by researchers, and the information required by policy makers and funders. Microbial biofilms present huge scientific, societal and economic opportunities and challenges. In order to identify key priorities that will help to advance the field, here we review questions from a pool submitted by the international biofilm research community and from practitioners working across industry, the environment and medicine. To avoid bias we used computational approaches to group questions and manage a voting and selection process. The outcome of the exercise is a set of 78 unique questions, categorized in six themes: (i) Biofilm control, disruption, prevention, management, treatment (13 questions); (ii) Resistance, persistence, tolerance, role of aggregation, immune interaction, relevance to infection (10 questions); (iii) Model systems, standards, regulatory, policy education, interdisciplinary approaches (15 questions); (iv) Polymicrobial, interactions, ecology, microbiome, phage (13 questions); (v) Clinical focus, chronic infection, detection, diagnostics (13 questions); and (vi) Matrix, lipids, capsule, metabolism, development, physiology, ecology, evolution environment, microbiome, community engineering (14 questions). The questions presented are intended to highlight opportunities, stimulate discussion and provide focus for researchers, funders and policy makers, informing future research, innovation and development strategy for biofilms and microbial communities. Published version MC, IF, CM, NN, RR, JSJ and JSW acknowledge support received from the BBSRC and Innovate UK, and funding from the National Biofilms Innovation Centre (BB/X002950/1). We acknowledge the continued support from the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) for the activities of the ESCMID Study Group on Biofilms. TC acknowledges support received from Fonds Wetenschappelijk Onderzoek – Vlaanderen (grant G066523 N) and ESCMID (ESCMID Study Group Grant). MA acknowledges funding support from NextGenerationEU (Biofilm management in water systems using hydrodynamic cavitation technology) and the Ministry of Education and Culture in Finland (HEAL: Healthier life with the comprehensive indoor hygiene concept; OKM/119/523/2021). EZG and CL were supported by the National Science Foundation (NSF OIA-1920954) and the National Institutes of Health (5P20GM103443-20). 2024-11-26T02:35:58Z 2024-11-26T02:35:58Z 2024 Journal Article Coenye, T., Ahonen, M., Anderson, S., Cámara, M., Chundi, P., Fields, M., Foidl, I., Gnimpieba, E. Z., Griffin, K., Hinks, J., Loka, A. R., Lushbough, C., MacPhee, C., Nater, N., Raval, R., Slater-Jefferies, J., Teo, P., Wilks, S., Yung, M. & Webb, J. S. (2024). Global challenges and microbial biofilms: identification of priority questions in biofilm research, innovation and policy. Biofilm, 8, 100210-. https://dx.doi.org/10.1016/j.bioflm.2024.100210 2590-2075 https://hdl.handle.net/10356/181343 10.1016/j.bioflm.2024.100210 39221168 2-s2.0-85198499659 8 100210 en Biofilm © 2024 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). application/pdf |
| spellingShingle | Engineering Microbial biofilms Global challenges Coenye, Tom Ahonen, Merja Anderson, Skip Cámara, Miguel Chundi, Parvathi Fields, Matthew Foidl, Ines Gnimpieba, Etienne Z. Griffin, Kristen Hinks, Jamie Loka, Anup R. Lushbough, Carol MacPhee, Cait Nater, Natasha Raval, Rasmita Slater-Jefferies, Jo Teo, Pauline Wilks, Sandra Yung, Maria Webb, Jeremy S. Global challenges and microbial biofilms: identification of priority questions in biofilm research, innovation and policy |
| title | Global challenges and microbial biofilms: identification of priority questions in biofilm research, innovation and policy |
| title_full | Global challenges and microbial biofilms: identification of priority questions in biofilm research, innovation and policy |
| title_fullStr | Global challenges and microbial biofilms: identification of priority questions in biofilm research, innovation and policy |
| title_full_unstemmed | Global challenges and microbial biofilms: identification of priority questions in biofilm research, innovation and policy |
| title_short | Global challenges and microbial biofilms: identification of priority questions in biofilm research, innovation and policy |
| title_sort | global challenges and microbial biofilms identification of priority questions in biofilm research innovation and policy |
| topic | Engineering Microbial biofilms Global challenges |
| url | https://hdl.handle.net/10356/181343 |
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