Quadri-wave lateral shearing interferometry: a versatile tool for quantitative phase imaging
Quantitative phase imaging (QPI) has emerged as a powerful tool in label-free bioimaging, in situ microstructure characterization for advanced manufacturing, and high-speed imaging of material property changes. Among various QPI methods, quadri-wave lateral shearing interferometry (QWLSI) stands out...
| প্রধান লেখক: | , , , |
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| অন্যান্য লেখক: | |
| বিন্যাস: | Journal Article |
| ভাষা: | English |
| প্রকাশিত: |
2025
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| বিষয়গুলি: | |
| অনলাইন ব্যবহার করুন: | https://hdl.handle.net/10356/182760 |
| _version_ | 1826110369036238848 |
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| author | Xie, Jun Xie, Hui Kong, Cheng Zhen Ling, Tong |
| author2 | School of Chemistry, Chemical Engineering and Biotechnology |
| author_facet | School of Chemistry, Chemical Engineering and Biotechnology Xie, Jun Xie, Hui Kong, Cheng Zhen Ling, Tong |
| author_sort | Xie, Jun |
| collection | NTU |
| description | Quantitative phase imaging (QPI) has emerged as a powerful tool in label-free bioimaging, in situ microstructure characterization for advanced manufacturing, and high-speed imaging of material property changes. Among various QPI methods, quadri-wave lateral shearing interferometry (QWLSI) stands out for its unique advantages in compactness, robustness, and high temporal resolution, making it an ideal choice for a wide range of applications. The compact design of QWLSI allows for easy integration with existing microscopy systems, while its robustness is manifested in the ability to maintain precise interferometric sensitivity even in high-vibration environments. Moreover, QWLSI also enables single-shot measurements that facilitate the capture of fast dynamic processes. This paper provides an in-depth exploration of the technical aspects of QWLSI, focusing on the evolution of its optical system and the primary algorithms used in wavefront reconstruction. The review also showcases significant applications of QWLSI, with a particular emphasis on its contributions to biomedical imaging. By discussing the advantages, limitations, and potential future developments of QWLSI, this paper aims to provide a comprehensive overview of this powerful QPI technique and its impact on various research fields. |
| first_indexed | 2025-03-09T10:02:37Z |
| format | Journal Article |
| id | ntu-10356/182760 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2025-03-09T10:02:37Z |
| publishDate | 2025 |
| record_format | dspace |
| spelling | ntu-10356/1827602025-02-28T15:32:15Z Quadri-wave lateral shearing interferometry: a versatile tool for quantitative phase imaging Xie, Jun Xie, Hui Kong, Cheng Zhen Ling, Tong School of Chemistry, Chemical Engineering and Biotechnology School of Electrical and Electronic Engineering Singapore National Eye Centre SERI-NTU Advanced Ocular Engineering (STANCE) Program Engineering Lateral shearing interferometry Quantitative phase imaging Quantitative phase imaging (QPI) has emerged as a powerful tool in label-free bioimaging, in situ microstructure characterization for advanced manufacturing, and high-speed imaging of material property changes. Among various QPI methods, quadri-wave lateral shearing interferometry (QWLSI) stands out for its unique advantages in compactness, robustness, and high temporal resolution, making it an ideal choice for a wide range of applications. The compact design of QWLSI allows for easy integration with existing microscopy systems, while its robustness is manifested in the ability to maintain precise interferometric sensitivity even in high-vibration environments. Moreover, QWLSI also enables single-shot measurements that facilitate the capture of fast dynamic processes. This paper provides an in-depth exploration of the technical aspects of QWLSI, focusing on the evolution of its optical system and the primary algorithms used in wavefront reconstruction. The review also showcases significant applications of QWLSI, with a particular emphasis on its contributions to biomedical imaging. By discussing the advantages, limitations, and potential future developments of QWLSI, this paper aims to provide a comprehensive overview of this powerful QPI technique and its impact on various research fields. Ministry of Education (MOE) Nanyang Technological University National Medical Research Council (NMRC) National Research Foundation (NRF) Published version Ministry of Education—Singapore (RS19/20, RG28/21, RG30/21); Nanyang Technological University (Startup Grant); National Medical Research Council (NMRC/CG/C010A/2017); National Research Foundation Singapore (NRF-NRFF14-2022-0005). 2025-02-24T06:12:27Z 2025-02-24T06:12:27Z 2024 Journal Article Xie, J., Xie, H., Kong, C. Z. & Ling, T. (2024). Quadri-wave lateral shearing interferometry: a versatile tool for quantitative phase imaging. Journal of the Optical Society of America A: Optics, Image Science, and Vision, 41(11), C137-C156. https://dx.doi.org/10.1364/JOSAA.534348 1084-7529 https://hdl.handle.net/10356/182760 10.1364/JOSAA.534348 39889087 2-s2.0-85209408943 11 41 C137 C156 en RS19/20 RG28/21 RG30/21 NTU SUG NMRC/CG/C010A/2017 NRF-NRFF14-2022-0005 Journal of the Optical Society of America A: Optics, Image Science, and Vision © 2024 Optica Publishing Group under the terms of the Optica Open Access Publishing Agreement. application/pdf |
| spellingShingle | Engineering Lateral shearing interferometry Quantitative phase imaging Xie, Jun Xie, Hui Kong, Cheng Zhen Ling, Tong Quadri-wave lateral shearing interferometry: a versatile tool for quantitative phase imaging |
| title | Quadri-wave lateral shearing interferometry: a versatile tool for quantitative phase imaging |
| title_full | Quadri-wave lateral shearing interferometry: a versatile tool for quantitative phase imaging |
| title_fullStr | Quadri-wave lateral shearing interferometry: a versatile tool for quantitative phase imaging |
| title_full_unstemmed | Quadri-wave lateral shearing interferometry: a versatile tool for quantitative phase imaging |
| title_short | Quadri-wave lateral shearing interferometry: a versatile tool for quantitative phase imaging |
| title_sort | quadri wave lateral shearing interferometry a versatile tool for quantitative phase imaging |
| topic | Engineering Lateral shearing interferometry Quantitative phase imaging |
| url | https://hdl.handle.net/10356/182760 |
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