Elucidating the structural and functional roles of filamentous proteins in immune signaling through cryo-EM helical reconstruction
Filamentous structures are fundamental to immune signaling, with cryo-EM helical reconstruction playing an important role in uncovering their architecture. While cytosolic CARD-containing proteins have been extensively studied, the oligomerisation and structural dynamics of nuclear CARDs remain poor...
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| Format: | Thesis-Doctor of Philosophy |
| Language: | English |
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Nanyang Technological University
2025
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| Online Access: | https://hdl.handle.net/10356/182803 |