Silver catalyzed multicomponent synthesis of aminoindolizines

A direct and efficient approach to 1-aminoindolizines through three component one pot reaction of heteroaryl aldehydes, second amines, and alkynes catalyzed by AgBF4 has been developed. This methodology provides rapid access to construct a diversified oriented library of indolizines.

Bibliographic Details
Main Author: Bai, Yaguang
Other Authors: Liu Xuewei
Format: Final Year Project (FYP)
Language:English
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10356/20852
Description
Summary:A direct and efficient approach to 1-aminoindolizines through three component one pot reaction of heteroaryl aldehydes, second amines, and alkynes catalyzed by AgBF4 has been developed. This methodology provides rapid access to construct a diversified oriented library of indolizines.