Refractive index measurement of single living cell using biophotonic chip
This project combines microfluidic and micro-optical technologies to develop an integrated biophotonic chip for single cell analysis. More specifically the effective refractive index (RI) of cells is determined. The microfluidic system serves as a tool for single living cell manipulation, while the...
| Main Authors: | , , , , |
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| Other Authors: | |
| Format: | Research Report |
| Published: |
2008
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/2927 |
| Summary: | This project combines microfluidic and micro-optical technologies to develop an integrated biophotonic chip for single cell analysis. More specifically the effective refractive index (RI) of cells is determined. The microfluidic system serves as a tool for single living cell manipulation, while the micro-optical system serves as a sensor to measure the effective RI of a single living cell in real time. By using RI as an indicator, any slight changes inside the cells can be detected. Therefore the biophotonic chip has a series of potential applications in many disease diagnostic devices in the future. |
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