Application of feature selection algorithms in gene expression data analysis

Although there are several causes of cancer, scientists have made a major breakthrough in discovering a number of candidate genes that associated with certain cancers. These genes, recognized as biomarkers, can contribute in early cancer diagnosis and prognosis and hence raise the possibility of...

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Bibliographic Details
Main Author: Wang, Ruiping.
Other Authors: Mao Kezhi
Format: Final Year Project (FYP)
Language:English
Published: 2010
Subjects:
Online Access:http://hdl.handle.net/10356/38899
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author Wang, Ruiping.
author2 Mao Kezhi
author_facet Mao Kezhi
Wang, Ruiping.
author_sort Wang, Ruiping.
collection NTU
description Although there are several causes of cancer, scientists have made a major breakthrough in discovering a number of candidate genes that associated with certain cancers. These genes, recognized as biomarkers, can contribute in early cancer diagnosis and prognosis and hence raise the possibility of curative surgery. The recent DNA microarray technology has made it possible for scientists and researchers to get a view of thousands of genes simultaneously. However, microarray data usually contains a huge number of genes (features) and a relatively small number of samples, which makes cancer prediction or classification based on microarray data more challenging. In this report, we consider the problem of applying feature selection techniques to select a small subset of informative biomarkers from DNA microarray data.
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spelling ntu-10356/388992023-07-07T16:37:07Z Application of feature selection algorithms in gene expression data analysis Wang, Ruiping. Mao Kezhi School of Electrical and Electronic Engineering DRNTU::Engineering::Electrical and electronic engineering::Computer hardware, software and systems DRNTU::Engineering::Computer science and engineering::Computing methodologies::Pattern recognition DRNTU::Engineering::Electrical and electronic engineering Although there are several causes of cancer, scientists have made a major breakthrough in discovering a number of candidate genes that associated with certain cancers. These genes, recognized as biomarkers, can contribute in early cancer diagnosis and prognosis and hence raise the possibility of curative surgery. The recent DNA microarray technology has made it possible for scientists and researchers to get a view of thousands of genes simultaneously. However, microarray data usually contains a huge number of genes (features) and a relatively small number of samples, which makes cancer prediction or classification based on microarray data more challenging. In this report, we consider the problem of applying feature selection techniques to select a small subset of informative biomarkers from DNA microarray data. Bachelor of Engineering 2010-05-20T06:19:00Z 2010-05-20T06:19:00Z 2010 2010 Final Year Project (FYP) http://hdl.handle.net/10356/38899 en Nanyang Technological University 74 p. application/pdf
spellingShingle DRNTU::Engineering::Electrical and electronic engineering::Computer hardware, software and systems
DRNTU::Engineering::Computer science and engineering::Computing methodologies::Pattern recognition
DRNTU::Engineering::Electrical and electronic engineering
Wang, Ruiping.
Application of feature selection algorithms in gene expression data analysis
title Application of feature selection algorithms in gene expression data analysis
title_full Application of feature selection algorithms in gene expression data analysis
title_fullStr Application of feature selection algorithms in gene expression data analysis
title_full_unstemmed Application of feature selection algorithms in gene expression data analysis
title_short Application of feature selection algorithms in gene expression data analysis
title_sort application of feature selection algorithms in gene expression data analysis
topic DRNTU::Engineering::Electrical and electronic engineering::Computer hardware, software and systems
DRNTU::Engineering::Computer science and engineering::Computing methodologies::Pattern recognition
DRNTU::Engineering::Electrical and electronic engineering
url http://hdl.handle.net/10356/38899
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