Receptor mediated adhesion under external stimuli
Many studies have shown that Epigallocatechin-3-gallate (EGCG) from green tea, exhibits therapeutic effects that inhibits cancer invasion and metastasis and affects cell proliferation and death Since cell adhesion is an important process that regulates cell migration, the effects of EGCG on cell...
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| Other Authors: | |
| Format: | Final Year Project (FYP) |
| Language: | English |
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2010
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| Online Access: | http://hdl.handle.net/10356/39563 |
| _version_ | 1811678630041878528 |
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| author | Ang, Ming Sheng |
| author2 | Chan Vincent |
| author_facet | Chan Vincent Ang, Ming Sheng |
| author_sort | Ang, Ming Sheng |
| collection | NTU |
| description | Many studies have shown that Epigallocatechin-3-gallate (EGCG) from green tea,
exhibits therapeutic effects that inhibits cancer invasion and metastasis and affects cell
proliferation and death Since cell adhesion is an important process that regulates cell
migration, the effects of EGCG on cell adhesion is investigated to understand more on its
therapeutic effects. This study demonstrated that HepG2 cell cultured with increasing
concentration of EGCG results in an increase in rate of adhesion contact area, degree of
cell deformation and average adhesion energy of cell. The inhibition of cell migration by
EGCG was also observed, which supports the evidence of therapeutic effects from
EGCG. |
| first_indexed | 2024-10-01T02:56:19Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/39563 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T02:56:19Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | ntu-10356/395632023-03-03T15:32:40Z Receptor mediated adhesion under external stimuli Ang, Ming Sheng Chan Vincent School of Chemical and Biomedical Engineering DRNTU::Engineering::Chemical engineering::Biotechnology Many studies have shown that Epigallocatechin-3-gallate (EGCG) from green tea, exhibits therapeutic effects that inhibits cancer invasion and metastasis and affects cell proliferation and death Since cell adhesion is an important process that regulates cell migration, the effects of EGCG on cell adhesion is investigated to understand more on its therapeutic effects. This study demonstrated that HepG2 cell cultured with increasing concentration of EGCG results in an increase in rate of adhesion contact area, degree of cell deformation and average adhesion energy of cell. The inhibition of cell migration by EGCG was also observed, which supports the evidence of therapeutic effects from EGCG. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2010-05-31T06:27:07Z 2010-05-31T06:27:07Z 2010 2010 Final Year Project (FYP) http://hdl.handle.net/10356/39563 en Nanyang Technological University 40 p. application/pdf |
| spellingShingle | DRNTU::Engineering::Chemical engineering::Biotechnology Ang, Ming Sheng Receptor mediated adhesion under external stimuli |
| title | Receptor mediated adhesion under external stimuli |
| title_full | Receptor mediated adhesion under external stimuli |
| title_fullStr | Receptor mediated adhesion under external stimuli |
| title_full_unstemmed | Receptor mediated adhesion under external stimuli |
| title_short | Receptor mediated adhesion under external stimuli |
| title_sort | receptor mediated adhesion under external stimuli |
| topic | DRNTU::Engineering::Chemical engineering::Biotechnology |
| url | http://hdl.handle.net/10356/39563 |
| work_keys_str_mv | AT angmingsheng receptormediatedadhesionunderexternalstimuli |