Dissection of mechanistic action of anticancer multidrug resistance reversal agents from a natural product library.
The phenomenon of multidrug resistant (MDR) ovarian cancer is a major obstacle to successful cancer treatment. Thapsigargin, a natural sesquiterpene lactone, has been studied for its MDR reversal effects against MDR cancers by inducing endoplasmic recticulum stress and cell death. In this study, we...
Main Author: | |
---|---|
Other Authors: | |
Format: | Final Year Project (FYP) |
Language: | English |
Published: |
2010
|
Subjects: | |
Online Access: | http://hdl.handle.net/10356/39580 |