Fe(III)- and Au(I)-catalyzed cyclization of arene-alkynes.
In this research report, Fe(III)- and Au(I)-catalyzed cyclizations of arene-alkynes were investigated. Au(I) catalyst has shown to be of very efficient catalytic activity for intramolecular hydroarylations of arene-alkynes with promising yields at mild conditions whether the alkyne is substituted by...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2010
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| Online Access: | http://hdl.handle.net/10356/39870 |
| _version_ | 1811687431893680128 |
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| author | Gao, Zhi Ming. |
| author2 | School of Physical and Mathematical Sciences |
| author_facet | School of Physical and Mathematical Sciences Gao, Zhi Ming. |
| author_sort | Gao, Zhi Ming. |
| collection | NTU |
| description | In this research report, Fe(III)- and Au(I)-catalyzed cyclizations of arene-alkynes were investigated. Au(I) catalyst has shown to be of very efficient catalytic activity for intramolecular hydroarylations of arene-alkynes with promising yields at mild conditions whether the alkyne is substituted by electron-withdrawing or electron-donating group. While Fe(III) was shown to be sensitive to the substitute on the alkyne moiety, electron-withdrawing group substituted alkynes did not proceed to cyclized products, but for the electron-donating group substituted arene-alkynes, Fe(III) catalyst showed as high efficiency as Au(I) catalyst. |
| first_indexed | 2024-10-01T05:16:13Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/39870 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:16:13Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | ntu-10356/398702023-02-28T23:14:39Z Fe(III)- and Au(I)-catalyzed cyclization of arene-alkynes. Gao, Zhi Ming. School of Physical and Mathematical Sciences Sunggak Kim DRNTU::Science::Chemistry::Organic chemistry::Heterocyclic compounds In this research report, Fe(III)- and Au(I)-catalyzed cyclizations of arene-alkynes were investigated. Au(I) catalyst has shown to be of very efficient catalytic activity for intramolecular hydroarylations of arene-alkynes with promising yields at mild conditions whether the alkyne is substituted by electron-withdrawing or electron-donating group. While Fe(III) was shown to be sensitive to the substitute on the alkyne moiety, electron-withdrawing group substituted alkynes did not proceed to cyclized products, but for the electron-donating group substituted arene-alkynes, Fe(III) catalyst showed as high efficiency as Au(I) catalyst. Bachelor of Science in Chemistry and Biological Chemistry 2010-06-07T06:33:28Z 2010-06-07T06:33:28Z 2010 2010 Final Year Project (FYP) http://hdl.handle.net/10356/39870 en 51 p. application/pdf |
| spellingShingle | DRNTU::Science::Chemistry::Organic chemistry::Heterocyclic compounds Gao, Zhi Ming. Fe(III)- and Au(I)-catalyzed cyclization of arene-alkynes. |
| title | Fe(III)- and Au(I)-catalyzed cyclization of arene-alkynes. |
| title_full | Fe(III)- and Au(I)-catalyzed cyclization of arene-alkynes. |
| title_fullStr | Fe(III)- and Au(I)-catalyzed cyclization of arene-alkynes. |
| title_full_unstemmed | Fe(III)- and Au(I)-catalyzed cyclization of arene-alkynes. |
| title_short | Fe(III)- and Au(I)-catalyzed cyclization of arene-alkynes. |
| title_sort | fe iii and au i catalyzed cyclization of arene alkynes |
| topic | DRNTU::Science::Chemistry::Organic chemistry::Heterocyclic compounds |
| url | http://hdl.handle.net/10356/39870 |
| work_keys_str_mv | AT gaozhiming feiiiandauicatalyzedcyclizationofarenealkynes |