Rare earth doped nanomaterials as potential contrast agents for optical/magnetic resonance imaging
The research work presented in this thesis focuses on the fabrication of rare earth (RE) doped nanomaterials as potential contrast agents for optical and magnetic resonance imaging. Owing to the sharp and intense emission obtained over the range of visible to the near-infrared regions in a wide vari...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
2010
|
| Subjects: | |
| Online Access: | https://hdl.handle.net/10356/40166 |
| _version_ | 1811686719421939712 |
|---|---|
| author | Das, Gautom Kumar |
| author2 | Tan Thatt Yang Timothy |
| author_facet | Tan Thatt Yang Timothy Das, Gautom Kumar |
| author_sort | Das, Gautom Kumar |
| collection | NTU |
| description | The research work presented in this thesis focuses on the fabrication of rare earth (RE) doped nanomaterials as potential contrast agents for optical and magnetic resonance imaging. Owing to the sharp and intense emission obtained over the range of visible to the near-infrared regions in a wide variety of hosts, RE-doped nanomaterials have attracted strong interests as contrast agents in bioimaging applications. The current study has successfully demonstrated the fabrication of fluorescent, and bifunctional magnetic-fluorescent RE-doped nanomaterials as contrast agents for bioimaging. At first, doping of different RE ions in yttrium oxide (Y2O3) host was investigated to fabricate the down- and up-conversion fluorescent nanoparticles. Effect of different synthesis parameters and type of RE dopants was investigated, and optimum conditions in relation to synthesis temperature, time, and concentration of RE dopants were reported and discussed. Spherical nanocrystals and nanorods could selectively be produced by varying different synthesis conditions. An evolution mechanism has been proposed to elucidate the morphology transformation to nanorods from nanocrystals. |
| first_indexed | 2024-10-01T05:04:53Z |
| format | Thesis |
| id | ntu-10356/40166 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:04:53Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | ntu-10356/401662023-03-03T16:02:06Z Rare earth doped nanomaterials as potential contrast agents for optical/magnetic resonance imaging Das, Gautom Kumar Tan Thatt Yang Timothy School of Chemical and Biomedical Engineering DRNTU::Engineering::Nanotechnology DRNTU::Engineering::Materials::Nanostructured materials The research work presented in this thesis focuses on the fabrication of rare earth (RE) doped nanomaterials as potential contrast agents for optical and magnetic resonance imaging. Owing to the sharp and intense emission obtained over the range of visible to the near-infrared regions in a wide variety of hosts, RE-doped nanomaterials have attracted strong interests as contrast agents in bioimaging applications. The current study has successfully demonstrated the fabrication of fluorescent, and bifunctional magnetic-fluorescent RE-doped nanomaterials as contrast agents for bioimaging. At first, doping of different RE ions in yttrium oxide (Y2O3) host was investigated to fabricate the down- and up-conversion fluorescent nanoparticles. Effect of different synthesis parameters and type of RE dopants was investigated, and optimum conditions in relation to synthesis temperature, time, and concentration of RE dopants were reported and discussed. Spherical nanocrystals and nanorods could selectively be produced by varying different synthesis conditions. An evolution mechanism has been proposed to elucidate the morphology transformation to nanorods from nanocrystals. DOCTOR OF PHILOSOPHY (SCBE) 2010-06-11T03:12:38Z 2010-06-11T03:12:38Z 2010 2010 Thesis Das, G. K. (2010). Rare earth doped nanomaterials as potential contrast agents for optical/magnetic resonance imaging. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/40166 10.32657/10356/40166 en 219 p. application/pdf |
| spellingShingle | DRNTU::Engineering::Nanotechnology DRNTU::Engineering::Materials::Nanostructured materials Das, Gautom Kumar Rare earth doped nanomaterials as potential contrast agents for optical/magnetic resonance imaging |
| title | Rare earth doped nanomaterials as potential contrast agents for optical/magnetic resonance imaging |
| title_full | Rare earth doped nanomaterials as potential contrast agents for optical/magnetic resonance imaging |
| title_fullStr | Rare earth doped nanomaterials as potential contrast agents for optical/magnetic resonance imaging |
| title_full_unstemmed | Rare earth doped nanomaterials as potential contrast agents for optical/magnetic resonance imaging |
| title_short | Rare earth doped nanomaterials as potential contrast agents for optical/magnetic resonance imaging |
| title_sort | rare earth doped nanomaterials as potential contrast agents for optical magnetic resonance imaging |
| topic | DRNTU::Engineering::Nanotechnology DRNTU::Engineering::Materials::Nanostructured materials |
| url | https://hdl.handle.net/10356/40166 |
| work_keys_str_mv | AT dasgautomkumar rareearthdopednanomaterialsaspotentialcontrastagentsforopticalmagneticresonanceimaging |