Synthesis and properties of amino- and guanidino-peptoid peptide nucleic acids
Peptide nucleic acid (PNA) is a synthetic mimic of DNA and RNA that can bind to complementary DNA and RNA with high affinity and sequence specificity. The structural simplicity, high hybridization affinity and in vivo stability of PNA have made it an attractive agent for antigene and antisense appli...
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| Format: | Thesis |
| Language: | English |
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2010
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| Online Access: | https://hdl.handle.net/10356/40210 |