Effects of age on spatial orientation neural network and default mode network : an fMRI study.
Age-related changes on the neural substrates of visuospatial processing were examined in the context of a line orientation judgment task in 23 younger and 21 older Japanese adults using functional magnetic resonance imaging (fMRI). Task induced deactivations were also employed to evaluate for age-re...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2011
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| Online Access: | http://hdl.handle.net/10356/44500 |
| _version_ | 1826111444898283520 |
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| author | Chong, Samuel Jun Quan. |
| author2 | School of Humanities and Social Sciences |
| author_facet | School of Humanities and Social Sciences Chong, Samuel Jun Quan. |
| author_sort | Chong, Samuel Jun Quan. |
| collection | NTU |
| description | Age-related changes on the neural substrates of visuospatial processing were examined in the context of a line orientation judgment task in 23 younger and 21 older Japanese adults using functional magnetic resonance imaging (fMRI). Task induced deactivations were also employed to evaluate for age-related changes in the default mode network. Group-specific activation maps for the visuospatial task and default mode network revealed differences between the younger and older subjects (e.g., bilateral precuneus activations in the younger subjects but right precuneus activations in the older subjects for the line task). However, these differences did not survive after controlling for normal brain atrophy and task difficulty suggesting relatively preserved visuospatial processing in normal aging. Implications and limitations of the study are discussed. |
| first_indexed | 2024-10-01T02:50:49Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/44500 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T02:50:49Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | ntu-10356/445002019-12-10T11:38:01Z Effects of age on spatial orientation neural network and default mode network : an fMRI study. Chong, Samuel Jun Quan. School of Humanities and Social Sciences Annabel Chen Shen-Hsing DRNTU::Social sciences::Psychology Age-related changes on the neural substrates of visuospatial processing were examined in the context of a line orientation judgment task in 23 younger and 21 older Japanese adults using functional magnetic resonance imaging (fMRI). Task induced deactivations were also employed to evaluate for age-related changes in the default mode network. Group-specific activation maps for the visuospatial task and default mode network revealed differences between the younger and older subjects (e.g., bilateral precuneus activations in the younger subjects but right precuneus activations in the older subjects for the line task). However, these differences did not survive after controlling for normal brain atrophy and task difficulty suggesting relatively preserved visuospatial processing in normal aging. Implications and limitations of the study are discussed. Bachelor of Arts 2011-06-02T02:06:37Z 2011-06-02T02:06:37Z 2011 2011 Final Year Project (FYP) http://hdl.handle.net/10356/44500 en Nanyang Technological University 48 p. application/pdf |
| spellingShingle | DRNTU::Social sciences::Psychology Chong, Samuel Jun Quan. Effects of age on spatial orientation neural network and default mode network : an fMRI study. |
| title | Effects of age on spatial orientation neural network and default mode network : an fMRI study. |
| title_full | Effects of age on spatial orientation neural network and default mode network : an fMRI study. |
| title_fullStr | Effects of age on spatial orientation neural network and default mode network : an fMRI study. |
| title_full_unstemmed | Effects of age on spatial orientation neural network and default mode network : an fMRI study. |
| title_short | Effects of age on spatial orientation neural network and default mode network : an fMRI study. |
| title_sort | effects of age on spatial orientation neural network and default mode network an fmri study |
| topic | DRNTU::Social sciences::Psychology |
| url | http://hdl.handle.net/10356/44500 |
| work_keys_str_mv | AT chongsamueljunquan effectsofageonspatialorientationneuralnetworkanddefaultmodenetworkanfmristudy |