Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters
Triple Negative Breast cancer (TNBC) is a newly studied subtype of breast cancer. Existing literature demonstrates that as cancer advances, the tumor cells will undergo epithelial-mesenchymal transition (EMT) to form secondary tumors at distant site. E-cadherin and Vimentin are biomarkers for epithe...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2011
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| Online Access: | http://hdl.handle.net/10356/45029 |
| _version_ | 1811681116932800512 |
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| author | Chai, Xiu Hui |
| author2 | School of Biological Sciences |
| author_facet | School of Biological Sciences Chai, Xiu Hui |
| author_sort | Chai, Xiu Hui |
| collection | NTU |
| description | Triple Negative Breast cancer (TNBC) is a newly studied subtype of breast cancer. Existing literature demonstrates that as cancer advances, the tumor cells will undergo epithelial-mesenchymal transition (EMT) to form secondary tumors at distant site. E-cadherin and Vimentin are biomarkers for epithelial and mesenchymal states respectively. β-catenin is involved in maintaining stable epithelial complex with E-cadherin and in signalling pathway implicated in tumorogenesis. |
| first_indexed | 2024-10-01T03:35:50Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/45029 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:35:50Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | ntu-10356/450292023-02-28T18:00:50Z Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters Chai, Xiu Hui School of Biological Sciences Jabed Iqbal DRNTU::Science::Medicine::Biosensors Triple Negative Breast cancer (TNBC) is a newly studied subtype of breast cancer. Existing literature demonstrates that as cancer advances, the tumor cells will undergo epithelial-mesenchymal transition (EMT) to form secondary tumors at distant site. E-cadherin and Vimentin are biomarkers for epithelial and mesenchymal states respectively. β-catenin is involved in maintaining stable epithelial complex with E-cadherin and in signalling pathway implicated in tumorogenesis. Bachelor of Science in Biological Sciences 2011-06-08T06:29:34Z 2011-06-08T06:29:34Z 2011 2011 Final Year Project (FYP) http://hdl.handle.net/10356/45029 en Nanyang Technological University 38 p. application/pdf |
| spellingShingle | DRNTU::Science::Medicine::Biosensors Chai, Xiu Hui Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters |
| title | Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters |
| title_full | Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters |
| title_fullStr | Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters |
| title_full_unstemmed | Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters |
| title_short | Study of biomarkers in the epithelial-mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters |
| title_sort | study of biomarkers in the epithelial mesenchymal transition of triple negative breast cancers and their associations with clinicopathological parameters |
| topic | DRNTU::Science::Medicine::Biosensors |
| url | http://hdl.handle.net/10356/45029 |
| work_keys_str_mv | AT chaixiuhui studyofbiomarkersintheepithelialmesenchymaltransitionoftriplenegativebreastcancersandtheirassociationswithclinicopathologicalparameters |