Self-assembled monolayer based micropatterns and their application in cell patterning
Microcontact printing using Self-Assembled Monolayers (SAMs) is a simple, yet powerful soft lithography technique and has extensive applications in micro- and nanofabrication. In this project, micropatterns of dot array and gratings are fabricated using SAM-based microcontact printing, followed by c...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Final Year Project (FYP) |
| Language: | English |
| Published: |
2011
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/45485 |
| _version_ | 1826120621022511104 |
|---|---|
| author | Ahuja, Tanvi |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Ahuja, Tanvi |
| author_sort | Ahuja, Tanvi |
| collection | NTU |
| description | Microcontact printing using Self-Assembled Monolayers (SAMs) is a simple, yet powerful soft lithography technique and has extensive applications in micro- and nanofabrication. In this project, micropatterns of dot array and gratings are fabricated using SAM-based microcontact printing, followed by coating of rare-earth nanoparticles. While the prime focus of this project is on pattern construction, cell attachment and viability are also investigated on these patterns, demonstrating an application of microcontact printing. Atomic Force Microscopy (AFM) and Scanning Electron Microscopy (SEM) are used to analyze patterns, and phase-contrast microscopy reveals cell adhesion behavior on these patterns. The results show that micropatterns of dot array and grating are successfully fabricated, with the shape of dot array being more perfectly reproduced than that of the grating. Both types of micropatterns enable good cell adhesion behavior, exhibiting their biocompatibility, and hence, emphasizing their potential for numerous applications in biomedical devices. |
| first_indexed | 2024-10-01T05:19:26Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/45485 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:19:26Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | ntu-10356/454852023-03-03T15:36:06Z Self-assembled monolayer based micropatterns and their application in cell patterning Ahuja, Tanvi School of Chemical and Biomedical Engineering Huang Ling DRNTU::Engineering::Nanotechnology Microcontact printing using Self-Assembled Monolayers (SAMs) is a simple, yet powerful soft lithography technique and has extensive applications in micro- and nanofabrication. In this project, micropatterns of dot array and gratings are fabricated using SAM-based microcontact printing, followed by coating of rare-earth nanoparticles. While the prime focus of this project is on pattern construction, cell attachment and viability are also investigated on these patterns, demonstrating an application of microcontact printing. Atomic Force Microscopy (AFM) and Scanning Electron Microscopy (SEM) are used to analyze patterns, and phase-contrast microscopy reveals cell adhesion behavior on these patterns. The results show that micropatterns of dot array and grating are successfully fabricated, with the shape of dot array being more perfectly reproduced than that of the grating. Both types of micropatterns enable good cell adhesion behavior, exhibiting their biocompatibility, and hence, emphasizing their potential for numerous applications in biomedical devices. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2011-06-14T03:03:05Z 2011-06-14T03:03:05Z 2011 2011 Final Year Project (FYP) http://hdl.handle.net/10356/45485 en Nanyang Technological University 44 p. application/pdf |
| spellingShingle | DRNTU::Engineering::Nanotechnology Ahuja, Tanvi Self-assembled monolayer based micropatterns and their application in cell patterning |
| title | Self-assembled monolayer based micropatterns and their application in cell patterning |
| title_full | Self-assembled monolayer based micropatterns and their application in cell patterning |
| title_fullStr | Self-assembled monolayer based micropatterns and their application in cell patterning |
| title_full_unstemmed | Self-assembled monolayer based micropatterns and their application in cell patterning |
| title_short | Self-assembled monolayer based micropatterns and their application in cell patterning |
| title_sort | self assembled monolayer based micropatterns and their application in cell patterning |
| topic | DRNTU::Engineering::Nanotechnology |
| url | http://hdl.handle.net/10356/45485 |
| work_keys_str_mv | AT ahujatanvi selfassembledmonolayerbasedmicropatternsandtheirapplicationincellpatterning |