Investigation of combinatory drug mix on cell behavior
Real-time combinatory drug responses on biological cells have become important for drug screenings with growing threat of diseases. Though rapid progress has been made in the field of biotechnology and pharmacy, the need to understand the effects of drug combinations, such as antibiotics and herbal...
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| Format: | Thesis |
| Language: | English |
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2011
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| Online Access: | https://hdl.handle.net/10356/45594 |
| _version_ | 1826127308414517248 |
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| author | Arora, Shuchi |
| author2 | Lim Chu Sing |
| author_facet | Lim Chu Sing Arora, Shuchi |
| author_sort | Arora, Shuchi |
| collection | NTU |
| description | Real-time combinatory drug responses on biological cells have become important for drug screenings with growing threat of diseases. Though rapid progress has been made in the field of biotechnology and pharmacy, the need to understand the effects of drug combinations, such as antibiotics and herbal medicines, on cells have become essential. Drug combinations are used to accelerate and/or increase the efficacy of a treatment. In case of infectious diseases, however, the predicaments of drug resistance prevail in the contemporary scenario. Drug combinations, in these cases, are mainly used to overcome such resistance by the disease causing pathogens. The present project created a unique system that can simultaneously investigate cell behavior exposed to a combinatory mixture of drugs. The system was aimed to conduct novel studies of combinatory drug performance on various cell types in vitro. Protocols for handling different cell types that require different culture conditions were established. |
| first_indexed | 2024-10-01T07:06:47Z |
| format | Thesis |
| id | ntu-10356/45594 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T07:06:47Z |
| publishDate | 2011 |
| record_format | dspace |
| spelling | ntu-10356/455942023-03-03T16:05:48Z Investigation of combinatory drug mix on cell behavior Arora, Shuchi Lim Chu Sing School of Chemical and Biomedical Engineering BioMedical Engineering Research Centre DRNTU::Science::Medicine::Pharmacy::Pharmaceutical technology DRNTU::Engineering::Chemical engineering::Biotechnology Real-time combinatory drug responses on biological cells have become important for drug screenings with growing threat of diseases. Though rapid progress has been made in the field of biotechnology and pharmacy, the need to understand the effects of drug combinations, such as antibiotics and herbal medicines, on cells have become essential. Drug combinations are used to accelerate and/or increase the efficacy of a treatment. In case of infectious diseases, however, the predicaments of drug resistance prevail in the contemporary scenario. Drug combinations, in these cases, are mainly used to overcome such resistance by the disease causing pathogens. The present project created a unique system that can simultaneously investigate cell behavior exposed to a combinatory mixture of drugs. The system was aimed to conduct novel studies of combinatory drug performance on various cell types in vitro. Protocols for handling different cell types that require different culture conditions were established. DOCTOR OF PHILOSOPHY (SCBE) 2011-06-15T06:21:50Z 2011-06-15T06:21:50Z 2011 2011 Thesis Arora, S. (2011). Investigation of combinatory drug mix on cell behavior. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/45594 10.32657/10356/45594 en 291 p. application/pdf |
| spellingShingle | DRNTU::Science::Medicine::Pharmacy::Pharmaceutical technology DRNTU::Engineering::Chemical engineering::Biotechnology Arora, Shuchi Investigation of combinatory drug mix on cell behavior |
| title | Investigation of combinatory drug mix on cell behavior |
| title_full | Investigation of combinatory drug mix on cell behavior |
| title_fullStr | Investigation of combinatory drug mix on cell behavior |
| title_full_unstemmed | Investigation of combinatory drug mix on cell behavior |
| title_short | Investigation of combinatory drug mix on cell behavior |
| title_sort | investigation of combinatory drug mix on cell behavior |
| topic | DRNTU::Science::Medicine::Pharmacy::Pharmaceutical technology DRNTU::Engineering::Chemical engineering::Biotechnology |
| url | https://hdl.handle.net/10356/45594 |
| work_keys_str_mv | AT arorashuchi investigationofcombinatorydrugmixoncellbehavior |