Study of homogenous assumption in epithelium tissue.

In past scientific studies focused on Monte Carlo simulations tissue models usually described as two layered. Later, tissue models became with three, six, and even nine sub-layers. Epidermis of skin tissues might be considered homogeneous and heterogeneous in terms of density, optical properties, an...

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主要作者: Oleg Obukhov.
其他作者: School of Chemical and Biomedical Engineering
格式: Final Year Project (FYP)
语言:English
出版: 2011
主题:
在线阅读:http://hdl.handle.net/10356/45636
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author Oleg Obukhov.
author2 School of Chemical and Biomedical Engineering
author_facet School of Chemical and Biomedical Engineering
Oleg Obukhov.
author_sort Oleg Obukhov.
collection NTU
description In past scientific studies focused on Monte Carlo simulations tissue models usually described as two layered. Later, tissue models became with three, six, and even nine sub-layers. Epidermis of skin tissues might be considered homogeneous and heterogeneous in terms of density, optical properties, and other parameters. For a past two semester, we had developed full cycle- method of relating different tissue model with heterogeneous tissue distribution to one with homogeneous. We had also investigated relationship between two types of tissue models and effect of optical properties on diffuse reflectance. With method developed, it is possible to determine homogeneous optical properties that generate same diffuse reflectance to heterogeneous same model. Once we had defined exact tissue model both with homogeneous and heterogeneous epidermal distribution, conducted Monte-Carlo Light Transport simulations to build array of diffuse reflectance corresponding to different scattering and abortion coefficient. Two different alignment of collecting fibres were set to obtain multiple diffuse reflectances depending on fibres position. After simulations were done, results were plotted in a graph and characterised with 9n and 10n polynomial. To relate diffuse reflectance to optical properties numerically, three different interpolation codes was developed to find single numerical solutions while relating different form of tissue models.
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spelling ntu-10356/456362023-03-03T15:32:19Z Study of homogenous assumption in epithelium tissue. Oleg Obukhov. School of Chemical and Biomedical Engineering Liu Quan DRNTU::Engineering::Bioengineering In past scientific studies focused on Monte Carlo simulations tissue models usually described as two layered. Later, tissue models became with three, six, and even nine sub-layers. Epidermis of skin tissues might be considered homogeneous and heterogeneous in terms of density, optical properties, and other parameters. For a past two semester, we had developed full cycle- method of relating different tissue model with heterogeneous tissue distribution to one with homogeneous. We had also investigated relationship between two types of tissue models and effect of optical properties on diffuse reflectance. With method developed, it is possible to determine homogeneous optical properties that generate same diffuse reflectance to heterogeneous same model. Once we had defined exact tissue model both with homogeneous and heterogeneous epidermal distribution, conducted Monte-Carlo Light Transport simulations to build array of diffuse reflectance corresponding to different scattering and abortion coefficient. Two different alignment of collecting fibres were set to obtain multiple diffuse reflectances depending on fibres position. After simulations were done, results were plotted in a graph and characterised with 9n and 10n polynomial. To relate diffuse reflectance to optical properties numerically, three different interpolation codes was developed to find single numerical solutions while relating different form of tissue models. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2011-06-15T08:45:30Z 2011-06-15T08:45:30Z 2011 2011 Final Year Project (FYP) http://hdl.handle.net/10356/45636 en Nanyang Technological University 76 p. application/pdf
spellingShingle DRNTU::Engineering::Bioengineering
Oleg Obukhov.
Study of homogenous assumption in epithelium tissue.
title Study of homogenous assumption in epithelium tissue.
title_full Study of homogenous assumption in epithelium tissue.
title_fullStr Study of homogenous assumption in epithelium tissue.
title_full_unstemmed Study of homogenous assumption in epithelium tissue.
title_short Study of homogenous assumption in epithelium tissue.
title_sort study of homogenous assumption in epithelium tissue
topic DRNTU::Engineering::Bioengineering
url http://hdl.handle.net/10356/45636
work_keys_str_mv AT olegobukhov studyofhomogenousassumptioninepitheliumtissue