Cell image segmentation for P53 immunohistochemistry in bladder inverted papilloma

171 p.

Bibliographic Details
Main Author: Zhao, Peng
Other Authors: Mao Kezhi
Format: Thesis
Published: 2011
Subjects:
Online Access:https://hdl.handle.net/10356/46968
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author Zhao, Peng
author2 Mao Kezhi
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Zhao, Peng
author_sort Zhao, Peng
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description 171 p.
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spelling ntu-10356/469682023-07-04T16:18:31Z Cell image segmentation for P53 immunohistochemistry in bladder inverted papilloma Zhao, Peng Mao Kezhi School of Electrical and Electronic Engineering DRNTU::Engineering::Electrical and electronic engineering 171 p. Bladder inverted papilloma is a histologically benign tumor located in the bladder, however it has also been reported that some bladder inverted papilloma could recur and develop into cancer. Diagnosis of bladder inverted papilloma primarily depends on biopsy, where p53 immunohistochemistry is the most frequently used marker. In clinical practice, diagnosis of bladder inverted papilloma is determined human-visually in terms of the percentage of positively stained cells in tissue samples, which is subjective or/and inconsistent. To enable quantitative, objective, and reproducible measurements, image analysis techniques are introduced to computerize cell analysis. The success of an automatic cell analysis system largely depends on the quality of segmentation. However, segmentation of cell images is far from easy due to the complex natures of histology images. Development of sophisticated cell image segmentation algorithms is necessary to ensure success of automatic cell analysis. This is the objective of the present study. DOCTOR OF PHILOSOPHY (EEE) 2011-12-27T05:50:36Z 2011-12-27T05:50:36Z 2007 2007 Thesis Zhao, P. (2007). Cell image segmentation for P53 immunohistochemistry in bladder inverted papilloma. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/46968 10.32657/10356/46968 Nanyang Technological University application/pdf
spellingShingle DRNTU::Engineering::Electrical and electronic engineering
Zhao, Peng
Cell image segmentation for P53 immunohistochemistry in bladder inverted papilloma
title Cell image segmentation for P53 immunohistochemistry in bladder inverted papilloma
title_full Cell image segmentation for P53 immunohistochemistry in bladder inverted papilloma
title_fullStr Cell image segmentation for P53 immunohistochemistry in bladder inverted papilloma
title_full_unstemmed Cell image segmentation for P53 immunohistochemistry in bladder inverted papilloma
title_short Cell image segmentation for P53 immunohistochemistry in bladder inverted papilloma
title_sort cell image segmentation for p53 immunohistochemistry in bladder inverted papilloma
topic DRNTU::Engineering::Electrical and electronic engineering
url https://hdl.handle.net/10356/46968
work_keys_str_mv AT zhaopeng cellimagesegmentationforp53immunohistochemistryinbladderinvertedpapilloma