Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots
79 p.
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Thesis |
| Published: |
Popular Science
2011
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/47229 |
| _version_ | 1826111716403970048 |
|---|---|
| author | Han Tun Aung |
| author2 | Subramanian Venkatraman |
| author_facet | Subramanian Venkatraman Han Tun Aung |
| author_sort | Han Tun Aung |
| collection | NTU |
| description | 79 p. |
| first_indexed | 2024-10-01T02:55:21Z |
| format | Thesis |
| id | ntu-10356/47229 |
| institution | Nanyang Technological University |
| last_indexed | 2024-10-01T02:55:21Z |
| publishDate | 2011 |
| publisher | Popular Science |
| record_format | dspace |
| spelling | ntu-10356/472292023-03-11T17:03:01Z Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots Han Tun Aung Subramanian Venkatraman School of Mechanical and Aerospace Engineering DRNTU::Engineering 79 p. In this research work, a novel controlled drug delivery system was studied. The system is made up of water insoluble, biodegradable polymers; poly (D,L lactide) (PDLLA) and poly (D,L-lactide-co-glycolide) (PLGA), dissolved in N-methyl-2-pyrrolidone (NMP). Such a polymer solution forms gel depot upon injection into the body fluids and the depot itself gradually degrades with time. A highly potent drug, 5-fluorouracil (5-FU) is incorporated into the depot to achieve the sustainable release profile. Master of Science (Biomedical Engineering) 2011-12-27T06:39:16Z 2011-12-27T06:39:16Z 2009 2009 Thesis http://hdl.handle.net/10356/47229 Nanyang Technological University application/pdf Popular Science |
| spellingShingle | DRNTU::Engineering Han Tun Aung Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots |
| title | Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots |
| title_full | Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots |
| title_fullStr | Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots |
| title_full_unstemmed | Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots |
| title_short | Drug delivery of 5-fluorouracil and biodegradation of injectable polymer-depots |
| title_sort | drug delivery of 5 fluorouracil and biodegradation of injectable polymer depots |
| topic | DRNTU::Engineering |
| url | http://hdl.handle.net/10356/47229 |
| work_keys_str_mv | AT hantunaung drugdeliveryof5fluorouracilandbiodegradationofinjectablepolymerdepots |