Microfluidic droplet formation and manipulations for microdroplets used as miniaturized laboratories

166 p.

Bibliographic Details
Main Author: Wang, Wei
Other Authors: Li Changming
Format: Thesis
Published: 2011
Subjects:
Online Access:https://hdl.handle.net/10356/47464
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author Wang, Wei
author2 Li Changming
author_facet Li Changming
Wang, Wei
author_sort Wang, Wei
collection NTU
description 166 p.
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institution Nanyang Technological University
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spelling ntu-10356/474642023-03-03T16:07:36Z Microfluidic droplet formation and manipulations for microdroplets used as miniaturized laboratories Wang, Wei Li Changming School of Chemical and Biomedical Engineering DRNTU::Engineering::Chemical engineering 166 p. As an emerging technique, Droplet Microfluidics has attracted great research and development interest for its capability to form micron sized droplets for applications in chemistry and biology. Microfluidic droplets are the basic cells in droplet microfluidic system and can be seen as isolated reactors compartmentalizing reactions and molecular processes. In order for the droplet microfluidic system to be configured according to functionality requirements, it is very essential to implement independent control of individual droplet. In this PhD thesis project, a series of droplet control techniques are developed and the manipulation mechanisms are investigated. With the developed techniques, compound droplets could be formed; targeted droplet could be trapped in microwell and droplet fusion could be on-demand triggered; trapped droplets could be on-demand released to microchannel for further analysis. The effective droplet manipulation schemes developed were expected to greatly facilitate the wide usage of droplets as naturally well-defined miniaturized laboratories. DOCTOR OF PHILOSOPHY (SCBE) 2011-12-27T08:22:49Z 2011-12-27T08:22:49Z 2010 2010 Thesis Wang, W. (2010). Microfluidic droplet formation and manipulations for microdroplets used as miniaturized laboratories. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/47464 10.32657/10356/47464 Nanyang Technological University application/pdf
spellingShingle DRNTU::Engineering::Chemical engineering
Wang, Wei
Microfluidic droplet formation and manipulations for microdroplets used as miniaturized laboratories
title Microfluidic droplet formation and manipulations for microdroplets used as miniaturized laboratories
title_full Microfluidic droplet formation and manipulations for microdroplets used as miniaturized laboratories
title_fullStr Microfluidic droplet formation and manipulations for microdroplets used as miniaturized laboratories
title_full_unstemmed Microfluidic droplet formation and manipulations for microdroplets used as miniaturized laboratories
title_short Microfluidic droplet formation and manipulations for microdroplets used as miniaturized laboratories
title_sort microfluidic droplet formation and manipulations for microdroplets used as miniaturized laboratories
topic DRNTU::Engineering::Chemical engineering
url https://hdl.handle.net/10356/47464
work_keys_str_mv AT wangwei microfluidicdropletformationandmanipulationsformicrodropletsusedasminiaturizedlaboratories