Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates
190 p.
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Format: | Thesis |
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2011
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Online Access: | https://hdl.handle.net/10356/47519 |
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author | Krisada Kittigowittana |
author2 | Roderick Wayland Bates |
author_facet | Roderick Wayland Bates Krisada Kittigowittana |
author_sort | Krisada Kittigowittana |
collection | NTU |
description | 190 p. |
first_indexed | 2024-10-01T03:45:15Z |
format | Thesis |
id | ntu-10356/47519 |
institution | Nanyang Technological University |
last_indexed | 2024-10-01T03:45:15Z |
publishDate | 2011 |
record_format | dspace |
spelling | ntu-10356/475192023-02-28T23:37:34Z Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates Krisada Kittigowittana Roderick Wayland Bates School of Physical and Mathematical Sciences DRNTU::Science::Biological sciences 190 p. Contrast agents with high relaxivity are needed for increasing the sensitivity of magnetic resonance imaging (MRI) for novel clinical and research applications. Therefore, we are developing a new class of oligomer-based contrast agents by incorporating multiple-gadolinium complexes into peptides of controlled length and structure. This allows synthesis of a library of Gd-peptides with different sequences, peptide length and number of Gd-chelates. Screening this library will enable selection of oligomers with desired properties. DOCTOR OF PHILOSOPHY (SPMS) 2011-12-27T08:32:31Z 2011-12-27T08:32:31Z 2010 2010 Thesis Krisada Kittigowittana. (2010). Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/47519 10.32657/10356/47519 Nanyang Technological University application/pdf |
spellingShingle | DRNTU::Science::Biological sciences Krisada Kittigowittana Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates |
title | Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates |
title_full | Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates |
title_fullStr | Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates |
title_full_unstemmed | Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates |
title_short | Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates |
title_sort | development of novel oligomer based intravascular contrast agents for mri using gadolinium chelates |
topic | DRNTU::Science::Biological sciences |
url | https://hdl.handle.net/10356/47519 |
work_keys_str_mv | AT krisadakittigowittana developmentofnoveloligomerbasedintravascularcontrastagentsformriusinggadoliniumchelates |