Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates

190 p.

Bibliographic Details
Main Author: Krisada Kittigowittana
Other Authors: Roderick Wayland Bates
Format: Thesis
Published: 2011
Subjects:
Online Access:https://hdl.handle.net/10356/47519
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author Krisada Kittigowittana
author2 Roderick Wayland Bates
author_facet Roderick Wayland Bates
Krisada Kittigowittana
author_sort Krisada Kittigowittana
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description 190 p.
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spelling ntu-10356/475192023-02-28T23:37:34Z Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates Krisada Kittigowittana Roderick Wayland Bates School of Physical and Mathematical Sciences DRNTU::Science::Biological sciences 190 p. Contrast agents with high relaxivity are needed for increasing the sensitivity of magnetic resonance imaging (MRI) for novel clinical and research applications. Therefore, we are developing a new class of oligomer-based contrast agents by incorporating multiple-gadolinium complexes into peptides of controlled length and structure. This allows synthesis of a library of Gd-peptides with different sequences, peptide length and number of Gd-chelates. Screening this library will enable selection of oligomers with desired properties. DOCTOR OF PHILOSOPHY (SPMS) 2011-12-27T08:32:31Z 2011-12-27T08:32:31Z 2010 2010 Thesis Krisada Kittigowittana. (2010). Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/47519 10.32657/10356/47519 Nanyang Technological University application/pdf
spellingShingle DRNTU::Science::Biological sciences
Krisada Kittigowittana
Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates
title Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates
title_full Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates
title_fullStr Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates
title_full_unstemmed Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates
title_short Development of novel oligomer-based intravascular contrast agents for MRI using gadolinium chelates
title_sort development of novel oligomer based intravascular contrast agents for mri using gadolinium chelates
topic DRNTU::Science::Biological sciences
url https://hdl.handle.net/10356/47519
work_keys_str_mv AT krisadakittigowittana developmentofnoveloligomerbasedintravascularcontrastagentsformriusinggadoliniumchelates