Hollow mesoporous silica nanoparticles for sustained cargo delivery
This study showed the comparison between conventional mesoporous silica nanoparticles (MSNPs) and hollow mesoporous silica nanoparticles (HMSNPs) in terms of their loading and releasing efficiency using Rhodamine-B (Rh.B) as hydrophilic model drug. The coating effect of polyethyleneimine (PEI) polym...
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מחברים אחרים: | |
פורמט: | Final Year Project (FYP) |
שפה: | English |
יצא לאור: |
2012
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גישה מקוונת: | http://hdl.handle.net/10356/48424 |
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author | Ling, Hwee Ting. |
author2 | School of Materials Science and Engineering |
author_facet | School of Materials Science and Engineering Ling, Hwee Ting. |
author_sort | Ling, Hwee Ting. |
collection | NTU |
description | This study showed the comparison between conventional mesoporous silica nanoparticles (MSNPs) and hollow mesoporous silica nanoparticles (HMSNPs) in terms of their loading and releasing efficiency using Rhodamine-B (Rh.B) as hydrophilic model drug. The coating effect of polyethyleneimine (PEI) polymer on the surface of the HMSNPs was also investigated and the results demonstrate that the PEI coating can help HMSNPs in achieving a sustained cargo release. The study employed the state-of-the-art techniques, e.g. TEM, BET, XRD, zeta-potential, FT-IR, and TGA, in characterizing the MSNPs and HMSNPs at different stages of the experiments and the obtained results were discussed accordingly. |
first_indexed | 2024-10-01T04:33:32Z |
format | Final Year Project (FYP) |
id | ntu-10356/48424 |
institution | Nanyang Technological University |
language | English |
last_indexed | 2024-10-01T04:33:32Z |
publishDate | 2012 |
record_format | dspace |
spelling | ntu-10356/484242023-03-04T15:39:35Z Hollow mesoporous silica nanoparticles for sustained cargo delivery Ling, Hwee Ting. School of Materials Science and Engineering Zhao Yanli DRNTU::Engineering::Materials::Nanostructured materials This study showed the comparison between conventional mesoporous silica nanoparticles (MSNPs) and hollow mesoporous silica nanoparticles (HMSNPs) in terms of their loading and releasing efficiency using Rhodamine-B (Rh.B) as hydrophilic model drug. The coating effect of polyethyleneimine (PEI) polymer on the surface of the HMSNPs was also investigated and the results demonstrate that the PEI coating can help HMSNPs in achieving a sustained cargo release. The study employed the state-of-the-art techniques, e.g. TEM, BET, XRD, zeta-potential, FT-IR, and TGA, in characterizing the MSNPs and HMSNPs at different stages of the experiments and the obtained results were discussed accordingly. Bachelor of Engineering (Materials Engineering) 2012-04-23T06:18:04Z 2012-04-23T06:18:04Z 2012 2012 Final Year Project (FYP) http://hdl.handle.net/10356/48424 en Nanyang Technological University 46 p. application/pdf |
spellingShingle | DRNTU::Engineering::Materials::Nanostructured materials Ling, Hwee Ting. Hollow mesoporous silica nanoparticles for sustained cargo delivery |
title | Hollow mesoporous silica nanoparticles for sustained cargo delivery |
title_full | Hollow mesoporous silica nanoparticles for sustained cargo delivery |
title_fullStr | Hollow mesoporous silica nanoparticles for sustained cargo delivery |
title_full_unstemmed | Hollow mesoporous silica nanoparticles for sustained cargo delivery |
title_short | Hollow mesoporous silica nanoparticles for sustained cargo delivery |
title_sort | hollow mesoporous silica nanoparticles for sustained cargo delivery |
topic | DRNTU::Engineering::Materials::Nanostructured materials |
url | http://hdl.handle.net/10356/48424 |
work_keys_str_mv | AT linghweeting hollowmesoporoussilicananoparticlesforsustainedcargodelivery |