Hollow mesoporous silica nanoparticles for sustained cargo delivery

This study showed the comparison between conventional mesoporous silica nanoparticles (MSNPs) and hollow mesoporous silica nanoparticles (HMSNPs) in terms of their loading and releasing efficiency using Rhodamine-B (Rh.B) as hydrophilic model drug. The coating effect of polyethyleneimine (PEI) polym...

תיאור מלא

מידע ביבליוגרפי
מחבר ראשי: Ling, Hwee Ting.
מחברים אחרים: School of Materials Science and Engineering
פורמט: Final Year Project (FYP)
שפה:English
יצא לאור: 2012
נושאים:
גישה מקוונת:http://hdl.handle.net/10356/48424
_version_ 1826117816786354176
author Ling, Hwee Ting.
author2 School of Materials Science and Engineering
author_facet School of Materials Science and Engineering
Ling, Hwee Ting.
author_sort Ling, Hwee Ting.
collection NTU
description This study showed the comparison between conventional mesoporous silica nanoparticles (MSNPs) and hollow mesoporous silica nanoparticles (HMSNPs) in terms of their loading and releasing efficiency using Rhodamine-B (Rh.B) as hydrophilic model drug. The coating effect of polyethyleneimine (PEI) polymer on the surface of the HMSNPs was also investigated and the results demonstrate that the PEI coating can help HMSNPs in achieving a sustained cargo release. The study employed the state-of-the-art techniques, e.g. TEM, BET, XRD, zeta-potential, FT-IR, and TGA, in characterizing the MSNPs and HMSNPs at different stages of the experiments and the obtained results were discussed accordingly.
first_indexed 2024-10-01T04:33:32Z
format Final Year Project (FYP)
id ntu-10356/48424
institution Nanyang Technological University
language English
last_indexed 2024-10-01T04:33:32Z
publishDate 2012
record_format dspace
spelling ntu-10356/484242023-03-04T15:39:35Z Hollow mesoporous silica nanoparticles for sustained cargo delivery Ling, Hwee Ting. School of Materials Science and Engineering Zhao Yanli DRNTU::Engineering::Materials::Nanostructured materials This study showed the comparison between conventional mesoporous silica nanoparticles (MSNPs) and hollow mesoporous silica nanoparticles (HMSNPs) in terms of their loading and releasing efficiency using Rhodamine-B (Rh.B) as hydrophilic model drug. The coating effect of polyethyleneimine (PEI) polymer on the surface of the HMSNPs was also investigated and the results demonstrate that the PEI coating can help HMSNPs in achieving a sustained cargo release. The study employed the state-of-the-art techniques, e.g. TEM, BET, XRD, zeta-potential, FT-IR, and TGA, in characterizing the MSNPs and HMSNPs at different stages of the experiments and the obtained results were discussed accordingly. Bachelor of Engineering (Materials Engineering) 2012-04-23T06:18:04Z 2012-04-23T06:18:04Z 2012 2012 Final Year Project (FYP) http://hdl.handle.net/10356/48424 en Nanyang Technological University 46 p. application/pdf
spellingShingle DRNTU::Engineering::Materials::Nanostructured materials
Ling, Hwee Ting.
Hollow mesoporous silica nanoparticles for sustained cargo delivery
title Hollow mesoporous silica nanoparticles for sustained cargo delivery
title_full Hollow mesoporous silica nanoparticles for sustained cargo delivery
title_fullStr Hollow mesoporous silica nanoparticles for sustained cargo delivery
title_full_unstemmed Hollow mesoporous silica nanoparticles for sustained cargo delivery
title_short Hollow mesoporous silica nanoparticles for sustained cargo delivery
title_sort hollow mesoporous silica nanoparticles for sustained cargo delivery
topic DRNTU::Engineering::Materials::Nanostructured materials
url http://hdl.handle.net/10356/48424
work_keys_str_mv AT linghweeting hollowmesoporoussilicananoparticlesforsustainedcargodelivery