Understanding of the influence of PVDF polymorphism on cell behaviour

Poly(vinylidene fluoride) (PVDF) is well known as its excellent electroactive properties (piezo-, pyro- and ferroelecticity), especially β crystalline phase. Also, PVDF is a good candidate of biomaterial as its high biocompatibility. These two valuable properties make PVDF getting highly attention f...

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Bibliographic Details
Main Author: Teow, Kai Soon.
Other Authors: School of Materials Science and Engineering
Format: Final Year Project (FYP)
Language:English
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10356/48430
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author Teow, Kai Soon.
author2 School of Materials Science and Engineering
author_facet School of Materials Science and Engineering
Teow, Kai Soon.
author_sort Teow, Kai Soon.
collection NTU
description Poly(vinylidene fluoride) (PVDF) is well known as its excellent electroactive properties (piezo-, pyro- and ferroelecticity), especially β crystalline phase. Also, PVDF is a good candidate of biomaterial as its high biocompatibility. These two valuable properties make PVDF getting highly attention from scientific community. However, the knowledge of cellular response against the phase transformation of PVDF is very limited. This is the driving force of this project. In this study, solvent casting was the main approach of fabricating PVDF films as dimethylformamide was chosen as solvent used. The mechanisms and trends of transformation between α- and β-PVDF were investigated by several characterization techniques, XRD, FTIR, DSC and SEM. Alternating of the crystallization temperature was selected as the method to trigger phase transformation. A trend of β-phase formation with lowering temperature was observed. Hence, the interaction between crystalline phase and cellular behavior was observed by cell-cultured of α-rich and β-rich PVDF films.
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spelling ntu-10356/484302023-03-04T15:34:42Z Understanding of the influence of PVDF polymorphism on cell behaviour Teow, Kai Soon. School of Materials Science and Engineering Ng Kee Woei DRNTU::Engineering::Materials::Biomaterials Poly(vinylidene fluoride) (PVDF) is well known as its excellent electroactive properties (piezo-, pyro- and ferroelecticity), especially β crystalline phase. Also, PVDF is a good candidate of biomaterial as its high biocompatibility. These two valuable properties make PVDF getting highly attention from scientific community. However, the knowledge of cellular response against the phase transformation of PVDF is very limited. This is the driving force of this project. In this study, solvent casting was the main approach of fabricating PVDF films as dimethylformamide was chosen as solvent used. The mechanisms and trends of transformation between α- and β-PVDF were investigated by several characterization techniques, XRD, FTIR, DSC and SEM. Alternating of the crystallization temperature was selected as the method to trigger phase transformation. A trend of β-phase formation with lowering temperature was observed. Hence, the interaction between crystalline phase and cellular behavior was observed by cell-cultured of α-rich and β-rich PVDF films. Bachelor of Engineering (Materials Engineering) 2012-04-23T07:21:42Z 2012-04-23T07:21:42Z 2012 2012 Final Year Project (FYP) http://hdl.handle.net/10356/48430 en Nanyang Technological University 35 p. application/pdf
spellingShingle DRNTU::Engineering::Materials::Biomaterials
Teow, Kai Soon.
Understanding of the influence of PVDF polymorphism on cell behaviour
title Understanding of the influence of PVDF polymorphism on cell behaviour
title_full Understanding of the influence of PVDF polymorphism on cell behaviour
title_fullStr Understanding of the influence of PVDF polymorphism on cell behaviour
title_full_unstemmed Understanding of the influence of PVDF polymorphism on cell behaviour
title_short Understanding of the influence of PVDF polymorphism on cell behaviour
title_sort understanding of the influence of pvdf polymorphism on cell behaviour
topic DRNTU::Engineering::Materials::Biomaterials
url http://hdl.handle.net/10356/48430
work_keys_str_mv AT teowkaisoon understandingoftheinfluenceofpvdfpolymorphismoncellbehaviour