Quest to reduce frustration : protein folding & emotional restoration.

A system in which unmet desired conditions exists is described as frustrated. Since forces will naturally seek to meet the desired conditions, in this study, the principle of reducing frustration as a driving force to natural processes is examined. Previous studies have applied the concept of fr...

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Bibliographic Details
Main Author: Nyam, Seow Wei.
Other Authors: Chew Lock Yue
Format: Final Year Project (FYP)
Language:English
Published: 2012
Subjects:
Online Access:http://hdl.handle.net/10356/49064
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author Nyam, Seow Wei.
author2 Chew Lock Yue
author_facet Chew Lock Yue
Nyam, Seow Wei.
author_sort Nyam, Seow Wei.
collection NTU
description A system in which unmet desired conditions exists is described as frustrated. Since forces will naturally seek to meet the desired conditions, in this study, the principle of reducing frustration as a driving force to natural processes is examined. Previous studies have applied the concept of frustration in the Ising Model. Findings supported the reduction of frustration as driving force to reach equilibrium state. It also suggests frustration and the inability to reach zero frustration (due to geometric constraints) as the cause of degenerate ground states. This study shall extend the study of frustration into the protein folding process and also back into the psychological sense, where the word originated from. Proteins are observed to fold themselves to reduce frustration but the different numbers of hydrophobic and hydrophilic residues, as well as the configuration (relative positions of residues) of the proteins, limit further reduction of frustration. The second part of the study looked for similar principles in frustration as an emotion experienced by human beings. It is observed that seeking to reduce frustration is a natural process and that constraints act as limitations to minimum frustration. In addition, the practice and effectiveness of counselling are supported, since it seeks to break constraints that limit the reduction of frustration.
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spelling ntu-10356/490642023-02-28T23:15:31Z Quest to reduce frustration : protein folding & emotional restoration. Nyam, Seow Wei. Chew Lock Yue School of Physical and Mathematical Sciences DRNTU::Science::General::Social aspects A system in which unmet desired conditions exists is described as frustrated. Since forces will naturally seek to meet the desired conditions, in this study, the principle of reducing frustration as a driving force to natural processes is examined. Previous studies have applied the concept of frustration in the Ising Model. Findings supported the reduction of frustration as driving force to reach equilibrium state. It also suggests frustration and the inability to reach zero frustration (due to geometric constraints) as the cause of degenerate ground states. This study shall extend the study of frustration into the protein folding process and also back into the psychological sense, where the word originated from. Proteins are observed to fold themselves to reduce frustration but the different numbers of hydrophobic and hydrophilic residues, as well as the configuration (relative positions of residues) of the proteins, limit further reduction of frustration. The second part of the study looked for similar principles in frustration as an emotion experienced by human beings. It is observed that seeking to reduce frustration is a natural process and that constraints act as limitations to minimum frustration. In addition, the practice and effectiveness of counselling are supported, since it seeks to break constraints that limit the reduction of frustration. Bachelor of Science in Physics 2012-05-14T07:25:50Z 2012-05-14T07:25:50Z 2012 2012 Final Year Project (FYP) http://hdl.handle.net/10356/49064 en 86 p. application/pdf
spellingShingle DRNTU::Science::General::Social aspects
Nyam, Seow Wei.
Quest to reduce frustration : protein folding & emotional restoration.
title Quest to reduce frustration : protein folding & emotional restoration.
title_full Quest to reduce frustration : protein folding & emotional restoration.
title_fullStr Quest to reduce frustration : protein folding & emotional restoration.
title_full_unstemmed Quest to reduce frustration : protein folding & emotional restoration.
title_short Quest to reduce frustration : protein folding & emotional restoration.
title_sort quest to reduce frustration protein folding emotional restoration
topic DRNTU::Science::General::Social aspects
url http://hdl.handle.net/10356/49064
work_keys_str_mv AT nyamseowwei questtoreducefrustrationproteinfoldingemotionalrestoration