HMGA2 protects induced pluripotent stem cell chromosomes against hydroxyurea-induced DNA damage.
High Motility Group A-T hook 2 (HMGA2) is a transcriptional regulator that binds to short AT rich sequences and is involved in global chromatin reorganization. HMGA2 is normally expressed during early development and is involved in specification of mesoderm-derived tissue. However, HMGA2 is re-expre...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2012
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| Online Access: | http://hdl.handle.net/10356/49246 |