Role of cargo receptors in Synphilin-1 mediated selective autophagy of protein aggregates.
The ANK-1 domain of synphilin-1 has been recently identified to able to impart autophagic clearance signals to certain disease-linked protein inclusions that were previously resistant to clearance by autophagy. To examine whether ANK1 cooperates with known cargo adaptors, p62 and NBR1, in mediating...
Main Author: | Lee, Karen Feng Yi. |
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Other Authors: | School of Biological Sciences |
Format: | Final Year Project (FYP) |
Language: | English |
Published: |
2012
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Subjects: | |
Online Access: | http://hdl.handle.net/10356/49281 |
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