Summary: | This report explores the use of silicone and gelatin matrixes to develop photoacoustic imaging phantoms to replicate biological tissues such as colon tissues. These two host medium houses Intralipid-20% and three types of ink (India ink, Evans Blue, Direct Reds 81) as scattering agent and absorbing agent respectively. Investigations using laser-induced photoacoustic configuration were carried out to characterize thermal diffusivity properties of the prepared samples at 632.8nm. In particular, the effects of increasing concentration of Intralipid-20% and increasing volume of encapsulated ink on thermal diffusivity properties were investigated upon.
Theoretical results of thermal diffusivity of the proposed samples ranges between 0.4 – 7.4 X 10-4 m2s-1, some of which are in agreement with thermal diffusivity values of colon phantoms and pig‘s stratum corneum found in past publications. Thermal diffusivity value of a fresh pig‘s colon tissue was found to be comparable (3 ±0.15 X 10-4 m2s-1) with previously reported values for colon phantom tissue, therefore validating the reliability of the PAS experimental setup in this investigation.
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