Investigation of liquid droplet and liposome spreading on smooth and patterned substrates

In this project, the spreading of liquid droplets and giant liposomes is investigated experimentally and numerically within the scope of continuum physics. Five liquids of different properties in their surface tension and viscosity are used, including deionized (DI) water, SDS (at the critical micel...

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Bibliographic Details
Main Author: Zhang, Ying
Other Authors: Chen Yan
Format: Thesis
Language:English
Published: 2012
Subjects:
Online Access:https://hdl.handle.net/10356/50363
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author Zhang, Ying
author2 Chen Yan
author_facet Chen Yan
Zhang, Ying
author_sort Zhang, Ying
collection NTU
description In this project, the spreading of liquid droplets and giant liposomes is investigated experimentally and numerically within the scope of continuum physics. Five liquids of different properties in their surface tension and viscosity are used, including deionized (DI) water, SDS (at the critical micelle concentration (CMC)), SDS (10% CMC), glycerol, and water-glycerol mixture (volume ratio 1:1). Liposomes are prepared from DOPC and the mixture of DOPA and DOPC (1:9). Isotropically patterned substrates and anisotropically patterned substrates are prepared to study the effect of surface patterns on spreading. The substrates for droplet spreading are fabricated on shape memory polymer through wrinkling, while those for liposome spreading are on silicon wafers by photolithography and dry etching. The wetting and spreading of liquid droplets and giant liposomes is characterized by the equilibrium contact angles, the equilibrium droplet/liposome dimensions, the dynamic change of contact angles, and the dynamic evolution of droplet/liposome dimensions.
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spelling ntu-10356/503632023-03-11T17:50:53Z Investigation of liquid droplet and liposome spreading on smooth and patterned substrates Zhang, Ying Chen Yan Fan Hui School of Mechanical and Aerospace Engineering Robotics Research Centre DRNTU::Engineering::Mechanical engineering In this project, the spreading of liquid droplets and giant liposomes is investigated experimentally and numerically within the scope of continuum physics. Five liquids of different properties in their surface tension and viscosity are used, including deionized (DI) water, SDS (at the critical micelle concentration (CMC)), SDS (10% CMC), glycerol, and water-glycerol mixture (volume ratio 1:1). Liposomes are prepared from DOPC and the mixture of DOPA and DOPC (1:9). Isotropically patterned substrates and anisotropically patterned substrates are prepared to study the effect of surface patterns on spreading. The substrates for droplet spreading are fabricated on shape memory polymer through wrinkling, while those for liposome spreading are on silicon wafers by photolithography and dry etching. The wetting and spreading of liquid droplets and giant liposomes is characterized by the equilibrium contact angles, the equilibrium droplet/liposome dimensions, the dynamic change of contact angles, and the dynamic evolution of droplet/liposome dimensions. DOCTOR OF PHILOSOPHY (MAE) 2012-06-01T04:38:34Z 2012-06-01T04:38:34Z 2012 2012 Thesis Zhang, Y. (2012). Investigation of liquid droplet and liposome spreading on smooth and patterned substrates. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/50363 10.32657/10356/50363 en 189 p. application/pdf
spellingShingle DRNTU::Engineering::Mechanical engineering
Zhang, Ying
Investigation of liquid droplet and liposome spreading on smooth and patterned substrates
title Investigation of liquid droplet and liposome spreading on smooth and patterned substrates
title_full Investigation of liquid droplet and liposome spreading on smooth and patterned substrates
title_fullStr Investigation of liquid droplet and liposome spreading on smooth and patterned substrates
title_full_unstemmed Investigation of liquid droplet and liposome spreading on smooth and patterned substrates
title_short Investigation of liquid droplet and liposome spreading on smooth and patterned substrates
title_sort investigation of liquid droplet and liposome spreading on smooth and patterned substrates
topic DRNTU::Engineering::Mechanical engineering
url https://hdl.handle.net/10356/50363
work_keys_str_mv AT zhangying investigationofliquiddropletandliposomespreadingonsmoothandpatternedsubstrates