Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease
Three disparate studies relating to the CD18 integrin are described in this thesis. Firstly, a particularly elusive CD18 mutation in an Leukocyte Adhesion Deficiency Type I (LAD-I) patient was studied. Genomic DNA and cDNA from an LAD-I patient and her family was analyzed and characterized. This mut...
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| Format: | Thesis |
| Language: | English |
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2012
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| Online Access: | https://hdl.handle.net/10356/50537 |
| _version_ | 1826109956074504192 |
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| author | Cher, Bernard Toh Hui |
| author2 | Law Sai-Kit Alex |
| author_facet | Law Sai-Kit Alex Cher, Bernard Toh Hui |
| author_sort | Cher, Bernard Toh Hui |
| collection | NTU |
| description | Three disparate studies relating to the CD18 integrin are described in this thesis. Firstly, a particularly elusive CD18 mutation in an Leukocyte Adhesion Deficiency Type I (LAD-I) patient was studied. Genomic DNA and cDNA from an LAD-I patient and her family was analyzed and characterized. This mutation was a gross deletion where the CD18 gene was truncated and joined to the next gene on the chromosome, PTTG1IP. |
| first_indexed | 2024-10-01T02:26:54Z |
| format | Thesis |
| id | ntu-10356/50537 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T02:26:54Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | ntu-10356/505372023-02-28T18:31:14Z Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease Cher, Bernard Toh Hui Law Sai-Kit Alex School of Biological Sciences DRNTU::Science::Biological sciences Three disparate studies relating to the CD18 integrin are described in this thesis. Firstly, a particularly elusive CD18 mutation in an Leukocyte Adhesion Deficiency Type I (LAD-I) patient was studied. Genomic DNA and cDNA from an LAD-I patient and her family was analyzed and characterized. This mutation was a gross deletion where the CD18 gene was truncated and joined to the next gene on the chromosome, PTTG1IP. DOCTOR OF PHILOSOPHY (SBS) 2012-06-14T06:24:26Z 2012-06-14T06:24:26Z 2011 2011 Thesis Cher, B. T. H. (2011). Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/50537 10.32657/10356/50537 en 253 p. application/pdf |
| spellingShingle | DRNTU::Science::Biological sciences Cher, Bernard Toh Hui Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease |
| title | Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease |
| title_full | Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease |
| title_fullStr | Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease |
| title_full_unstemmed | Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease |
| title_short | Three disparate studies on the CD18 integrin : expression and biological functions of the human CD18 integrin in health and disease |
| title_sort | three disparate studies on the cd18 integrin expression and biological functions of the human cd18 integrin in health and disease |
| topic | DRNTU::Science::Biological sciences |
| url | https://hdl.handle.net/10356/50537 |
| work_keys_str_mv | AT cherbernardtohhui threedisparatestudiesonthecd18integrinexpressionandbiologicalfunctionsofthehumancd18integrininhealthanddisease |