Green tea catechin, EGCG, modulates mitochondrial dynamics in dopaminergic neurons of α-synuclein transgenic flies resulting in mobility improvement.
Parkinson’s disease (PD) is characterized pathologically by the hallmark presence of Lewy bodies, which are intraneuronal inclusions comprised of chiefly α-synuclein. Studies have illustrated an association between the toxicity induced by over-expression of α-synuclein and PD-related locomotive defi...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2012
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| Online Access: | http://hdl.handle.net/10356/50655 |