Scientific visualization of DNA sequence matching in large-scale genomics sequencing

OligoSpawn is a Linux-based software package for DNA pattern discovery. OligoSpawn can be used to discover two types of oligos (short DNA patterns of 20-50 bases long), namely unique and popular oligos, from large databases of gene sequences. The purpose of this project is to add a GUI for OligoSpaw...

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Bibliographic Details
Main Author: Raina, Priyanka
Other Authors: School of Computer Engineering
Format: Final Year Project (FYP)
Language:English
Published: 2013
Subjects:
Online Access:http://hdl.handle.net/10356/51992
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author Raina, Priyanka
author2 School of Computer Engineering
author_facet School of Computer Engineering
Raina, Priyanka
author_sort Raina, Priyanka
collection NTU
description OligoSpawn is a Linux-based software package for DNA pattern discovery. OligoSpawn can be used to discover two types of oligos (short DNA patterns of 20-50 bases long), namely unique and popular oligos, from large databases of gene sequences. The purpose of this project is to add a GUI for OligoSpawn, and then extend the OligoSpawn GUI to visualize the mapping of large numbers of short DNA reads from next-generation sequencing (NGS) to reference genomes. The GUI is being constructed in Python using PyPE as the IDE, wxpython as the GUI-building toolkit and Swig to wrap around the C and C++ based backend code. The report is segmented into three major sections: Overview of the software and concepts utilized; Techniques employed during implementation and the Final results.
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spelling ntu-10356/519922023-03-03T20:29:22Z Scientific visualization of DNA sequence matching in large-scale genomics sequencing Raina, Priyanka School of Computer Engineering Zheng Jie DRNTU::Engineering::Computer science and engineering::Information systems::Information interfaces and presentation OligoSpawn is a Linux-based software package for DNA pattern discovery. OligoSpawn can be used to discover two types of oligos (short DNA patterns of 20-50 bases long), namely unique and popular oligos, from large databases of gene sequences. The purpose of this project is to add a GUI for OligoSpawn, and then extend the OligoSpawn GUI to visualize the mapping of large numbers of short DNA reads from next-generation sequencing (NGS) to reference genomes. The GUI is being constructed in Python using PyPE as the IDE, wxpython as the GUI-building toolkit and Swig to wrap around the C and C++ based backend code. The report is segmented into three major sections: Overview of the software and concepts utilized; Techniques employed during implementation and the Final results. Bachelor of Engineering (Computer Science) 2013-04-19T02:48:38Z 2013-04-19T02:48:38Z 2013 2013 Final Year Project (FYP) http://hdl.handle.net/10356/51992 en Nanyang Technological University 65 p. application/pdf
spellingShingle DRNTU::Engineering::Computer science and engineering::Information systems::Information interfaces and presentation
Raina, Priyanka
Scientific visualization of DNA sequence matching in large-scale genomics sequencing
title Scientific visualization of DNA sequence matching in large-scale genomics sequencing
title_full Scientific visualization of DNA sequence matching in large-scale genomics sequencing
title_fullStr Scientific visualization of DNA sequence matching in large-scale genomics sequencing
title_full_unstemmed Scientific visualization of DNA sequence matching in large-scale genomics sequencing
title_short Scientific visualization of DNA sequence matching in large-scale genomics sequencing
title_sort scientific visualization of dna sequence matching in large scale genomics sequencing
topic DRNTU::Engineering::Computer science and engineering::Information systems::Information interfaces and presentation
url http://hdl.handle.net/10356/51992
work_keys_str_mv AT rainapriyanka scientificvisualizationofdnasequencematchinginlargescalegenomicssequencing