3D osteoarthritic model.
Osteoarthritis is the most common form of arthritis mainly affecting population of the age 60 and above. Due to low self-recovery ability of cartilage, extrinsic methods such as drug delivery and artificial cartilage replacement are needed to promote the healing process of osteoarthritic cartilage....
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
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2013
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| Online Access: | http://hdl.handle.net/10356/54316 |
| _version_ | 1811680956743942144 |
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| author | Ng, Ling Yen. |
| author2 | Wang Dongan |
| author_facet | Wang Dongan Ng, Ling Yen. |
| author_sort | Ng, Ling Yen. |
| collection | NTU |
| description | Osteoarthritis is the most common form of arthritis mainly affecting population of the age 60 and above. Due to low self-recovery ability of cartilage, extrinsic methods such as drug delivery and artificial cartilage replacement are needed to promote the healing process of osteoarthritic cartilage. The most widely used diseased models in current drug screening study including animal models, monolayer models and 3D scaffold models. However, there are a few disadvantages on each of the system, for instance, ethical issue on animal models, dedifferentiation problem on 2D models, and low purity problem on 3D scaffold models. |
| first_indexed | 2024-10-01T03:33:17Z |
| format | Thesis |
| id | ntu-10356/54316 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T03:33:17Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/543162023-03-03T15:59:12Z 3D osteoarthritic model. Ng, Ling Yen. Wang Dongan School of Chemical and Biomedical Engineering DRNTU::Engineering::Bioengineering Osteoarthritis is the most common form of arthritis mainly affecting population of the age 60 and above. Due to low self-recovery ability of cartilage, extrinsic methods such as drug delivery and artificial cartilage replacement are needed to promote the healing process of osteoarthritic cartilage. The most widely used diseased models in current drug screening study including animal models, monolayer models and 3D scaffold models. However, there are a few disadvantages on each of the system, for instance, ethical issue on animal models, dedifferentiation problem on 2D models, and low purity problem on 3D scaffold models. Master of Science (Biomedical Engineering) 2013-06-19T02:43:02Z 2013-06-19T02:43:02Z 2013 2013 Thesis http://hdl.handle.net/10356/54316 en 64 p. application/pdf |
| spellingShingle | DRNTU::Engineering::Bioengineering Ng, Ling Yen. 3D osteoarthritic model. |
| title | 3D osteoarthritic model. |
| title_full | 3D osteoarthritic model. |
| title_fullStr | 3D osteoarthritic model. |
| title_full_unstemmed | 3D osteoarthritic model. |
| title_short | 3D osteoarthritic model. |
| title_sort | 3d osteoarthritic model |
| topic | DRNTU::Engineering::Bioengineering |
| url | http://hdl.handle.net/10356/54316 |
| work_keys_str_mv | AT nglingyen 3dosteoarthriticmodel |