The role of growth factor receptor bound protein 2 (GRB2) in gain of function of mutant p53.
Mutation and inactivation of p53 is almost a universal feature in human cancer. That has made p53 one of the most studied proteins. Several mutant p53 have been shown to have dominant phenotype over wild-type p53. Studies have attributed the ability of mutant p53 to acquire oncogenic properties such...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2013
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| Online Access: | http://hdl.handle.net/10356/54806 |