Design, synthesis and bio-application of functional mesoporous silica nanoparticle
The research work concentrated on the design, synthesis and biological application of functional mesoporous silica nanoparticles. Through novel functionalization, several mesoporous silica nanoparticle (MSNP) based systems aiming at different biological applications, including drug/gene co-delivery,...
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| Format: | Thesis |
| Language: | English |
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2013
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| Online Access: | https://hdl.handle.net/10356/54992 |
| _version_ | 1811678225097555968 |
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| author | Ma, Xing |
| author2 | School of Materials Science & Engineering |
| author_facet | School of Materials Science & Engineering Ma, Xing |
| author_sort | Ma, Xing |
| collection | NTU |
| description | The research work concentrated on the design, synthesis and biological application of functional mesoporous silica nanoparticles. Through novel functionalization, several mesoporous silica nanoparticle (MSNP) based systems aiming at different biological applications, including drug/gene co-delivery, photodynamic therapy (PDT) and bio-image, are designed and fabricated. A variety of techniques of both materials and chemical science are used to fully characterize the functional MSNP before application in the biological system. By in vitro and in vivo experiments with cancer cell lines and zebra fish, the effectiveness of these functional MSNP based nano-systems are verified. |
| first_indexed | 2024-10-01T02:49:52Z |
| format | Thesis |
| id | ntu-10356/54992 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T02:49:52Z |
| publishDate | 2013 |
| record_format | dspace |
| spelling | ntu-10356/549922023-03-04T16:41:41Z Design, synthesis and bio-application of functional mesoporous silica nanoparticle Ma, Xing School of Materials Science & Engineering Zhao Yanli DRNTU::Engineering::Materials The research work concentrated on the design, synthesis and biological application of functional mesoporous silica nanoparticles. Through novel functionalization, several mesoporous silica nanoparticle (MSNP) based systems aiming at different biological applications, including drug/gene co-delivery, photodynamic therapy (PDT) and bio-image, are designed and fabricated. A variety of techniques of both materials and chemical science are used to fully characterize the functional MSNP before application in the biological system. By in vitro and in vivo experiments with cancer cell lines and zebra fish, the effectiveness of these functional MSNP based nano-systems are verified. DOCTOR OF PHILOSOPHY (MSE) 2013-11-21T05:55:53Z 2013-11-21T05:55:53Z 2013 2013 Thesis Ma, X. (2013). Design, synthesis and bio-application of functional mesoporous silica nanoparticle. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/54992 10.32657/10356/54992 en 177 p. application/pdf |
| spellingShingle | DRNTU::Engineering::Materials Ma, Xing Design, synthesis and bio-application of functional mesoporous silica nanoparticle |
| title | Design, synthesis and bio-application of functional mesoporous silica nanoparticle |
| title_full | Design, synthesis and bio-application of functional mesoporous silica nanoparticle |
| title_fullStr | Design, synthesis and bio-application of functional mesoporous silica nanoparticle |
| title_full_unstemmed | Design, synthesis and bio-application of functional mesoporous silica nanoparticle |
| title_short | Design, synthesis and bio-application of functional mesoporous silica nanoparticle |
| title_sort | design synthesis and bio application of functional mesoporous silica nanoparticle |
| topic | DRNTU::Engineering::Materials |
| url | https://hdl.handle.net/10356/54992 |
| work_keys_str_mv | AT maxing designsynthesisandbioapplicationoffunctionalmesoporoussilicananoparticle |