Modeling of the cancer thermal therapies from the perspective of parametric sensitivity and improved treatment planning
The scope of this thesis covers the improved efficacy of the thermal therapies of capacitive hyperthermia and radiofrequency ablation (RFA). Additionally, it deals with the simulation of bioheat transfer with a novel numerical method that makes use of its meshless characteristic to provide the optim...
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| Định dạng: | Luận văn |
| Ngôn ngữ: | English |
| Được phát hành: |
2014
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| Những chủ đề: | |
| Truy cập trực tuyến: | https://hdl.handle.net/10356/55390 |
| _version_ | 1826111658153476096 |
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| author | Muhammad Jamil |
| author2 | Ng Yin Kwee, Eddie |
| author_facet | Ng Yin Kwee, Eddie Muhammad Jamil |
| author_sort | Muhammad Jamil |
| collection | NTU |
| description | The scope of this thesis covers the improved efficacy of the thermal therapies of capacitive hyperthermia and radiofrequency ablation (RFA). Additionally, it deals with the simulation of bioheat transfer with a novel numerical method that makes use of its meshless characteristic to provide the optimum simulation results. For capacitive hyperthermia, the effect of electrothermal parameters as well as physical parameters was quantified and regression based prediction model was formulated. Additionally, a novel meshless method known as Radial Basis Collocation Method (RBCM) has been applied to simulate the heterogeneous conduction and bioheat transfer problem. Research was carried out to analyze the efficacy of radiofrequency ablation (RFA) for varying electrothermal parameters under fixed temperature control and their combined effect was analyzed quantitatively in different tissues. Additionally, the effect of electrothermal parameters for concentric tumour model was analyzed under automatic temperature control. Simplified models models were utilized for prediction of therapeutic outcome. |
| first_indexed | 2024-10-01T02:54:24Z |
| format | Thesis |
| id | ntu-10356/55390 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T02:54:24Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | ntu-10356/553902023-03-11T17:31:18Z Modeling of the cancer thermal therapies from the perspective of parametric sensitivity and improved treatment planning Muhammad Jamil Ng Yin Kwee, Eddie School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering The scope of this thesis covers the improved efficacy of the thermal therapies of capacitive hyperthermia and radiofrequency ablation (RFA). Additionally, it deals with the simulation of bioheat transfer with a novel numerical method that makes use of its meshless characteristic to provide the optimum simulation results. For capacitive hyperthermia, the effect of electrothermal parameters as well as physical parameters was quantified and regression based prediction model was formulated. Additionally, a novel meshless method known as Radial Basis Collocation Method (RBCM) has been applied to simulate the heterogeneous conduction and bioheat transfer problem. Research was carried out to analyze the efficacy of radiofrequency ablation (RFA) for varying electrothermal parameters under fixed temperature control and their combined effect was analyzed quantitatively in different tissues. Additionally, the effect of electrothermal parameters for concentric tumour model was analyzed under automatic temperature control. Simplified models models were utilized for prediction of therapeutic outcome. DOCTOR OF PHILOSOPHY (MAE) 2014-02-26T03:01:57Z 2014-02-26T03:01:57Z 2014 2014 Thesis Muhammad Jamil. (2014). Modeling of the cancer thermal therapies from the perspective of parametric sensitivity and improved treatment planning. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/55390 10.32657/10356/55390 en 222 p. application/pdf |
| spellingShingle | DRNTU::Engineering::Mechanical engineering Muhammad Jamil Modeling of the cancer thermal therapies from the perspective of parametric sensitivity and improved treatment planning |
| title | Modeling of the cancer thermal therapies from the perspective of parametric sensitivity and improved treatment planning |
| title_full | Modeling of the cancer thermal therapies from the perspective of parametric sensitivity and improved treatment planning |
| title_fullStr | Modeling of the cancer thermal therapies from the perspective of parametric sensitivity and improved treatment planning |
| title_full_unstemmed | Modeling of the cancer thermal therapies from the perspective of parametric sensitivity and improved treatment planning |
| title_short | Modeling of the cancer thermal therapies from the perspective of parametric sensitivity and improved treatment planning |
| title_sort | modeling of the cancer thermal therapies from the perspective of parametric sensitivity and improved treatment planning |
| topic | DRNTU::Engineering::Mechanical engineering |
| url | https://hdl.handle.net/10356/55390 |
| work_keys_str_mv | AT muhammadjamil modelingofthecancerthermaltherapiesfromtheperspectiveofparametricsensitivityandimprovedtreatmentplanning |