Characterization of zebrafish IKK2 mutants generated by zinc finger nucleases
IκB kinase β (IKK2/IKKβ) is known as a master regulator of NF-κB signaling, which mediates stress, immune and inflammatory responses. Unfortunately, embryonic lethality in IKK2-deficient mice hinders studies of zygotic IKK2 function beyond embryonic stages. Although conditional knockout mice have be...
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Final Year Project (FYP) |
| Language: | English |
| Published: |
2014
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/59585 |