How metastatic cancer cells become resistant to apoptosis
Breast cancer is the second most common type cancer in women. This paper shows that the metastatic breast cancer cells present stronger drug resistance compared to its origin cancer cells. The mechanism of the drug resistance of metastatic cancer cells were studied by using MTT assay, Immunostaining...
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| Format: | Final Year Project (FYP) |
| Language: | English |
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2014
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| Online Access: | http://hdl.handle.net/10356/61634 |
| _version_ | 1826120108763774976 |
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| author | Zhou, Zhicai |
| author2 | School of Chemical and Biomedical Engineering |
| author_facet | School of Chemical and Biomedical Engineering Zhou, Zhicai |
| author_sort | Zhou, Zhicai |
| collection | NTU |
| description | Breast cancer is the second most common type cancer in women. This paper shows that the metastatic breast cancer cells present stronger drug resistance compared to its origin cancer cells. The mechanism of the drug resistance of metastatic cancer cells were studied by using MTT assay, Immunostaining and Western Blot. Results showed the mechanism of this drug resistance mainly rise from the high ABC transporter and SOD2 expression. |
| first_indexed | 2024-10-01T05:11:08Z |
| format | Final Year Project (FYP) |
| id | ntu-10356/61634 |
| institution | Nanyang Technological University |
| language | English |
| last_indexed | 2024-10-01T05:11:08Z |
| publishDate | 2014 |
| record_format | dspace |
| spelling | ntu-10356/616342023-03-03T15:35:54Z How metastatic cancer cells become resistant to apoptosis Zhou, Zhicai School of Chemical and Biomedical Engineering Kathy Luo Qian DRNTU::Science::Medicine::Biomedical engineering Breast cancer is the second most common type cancer in women. This paper shows that the metastatic breast cancer cells present stronger drug resistance compared to its origin cancer cells. The mechanism of the drug resistance of metastatic cancer cells were studied by using MTT assay, Immunostaining and Western Blot. Results showed the mechanism of this drug resistance mainly rise from the high ABC transporter and SOD2 expression. Bachelor of Engineering (Chemical and Biomolecular Engineering) 2014-06-30T05:08:26Z 2014-06-30T05:08:26Z 2014 2014 Final Year Project (FYP) http://hdl.handle.net/10356/61634 en Nanyang Technological University 49 p. application/pdf |
| spellingShingle | DRNTU::Science::Medicine::Biomedical engineering Zhou, Zhicai How metastatic cancer cells become resistant to apoptosis |
| title | How metastatic cancer cells become resistant to apoptosis |
| title_full | How metastatic cancer cells become resistant to apoptosis |
| title_fullStr | How metastatic cancer cells become resistant to apoptosis |
| title_full_unstemmed | How metastatic cancer cells become resistant to apoptosis |
| title_short | How metastatic cancer cells become resistant to apoptosis |
| title_sort | how metastatic cancer cells become resistant to apoptosis |
| topic | DRNTU::Science::Medicine::Biomedical engineering |
| url | http://hdl.handle.net/10356/61634 |
| work_keys_str_mv | AT zhouzhicai howmetastaticcancercellsbecomeresistanttoapoptosis |