Design and examine oligonucleotide structures as inhibitors to topoisomerase IV

Design and examine oligonucleotide structures as inhibitors to topoisomerase IV

Topoisomerase IV is an enzyme that exclusively presents in prokaryotic cells and is mainly responsible for unwinding interlocked DNA strands at the final stage of prokaryotic replication. Since it is a prokaryotic enzyme, various types of quinolones were developed in the past as inhibitors of topo I...

书目详细资料
主要作者:	Guo, Juanjuan
其他作者:	Shao Fangwei
格式:	Thesis
语言:	English
出版:	2014
主题:	DRNTU::Science
在线阅读:	http://hdl.handle.net/10356/61861

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