Engineering cleavage efficient 2A peptides for enhancing monoclonal antibody expression in CHO cells

Engineering cleavage efficient 2A peptides for enhancing monoclonal antibody expression in CHO cells

2A peptides are derived from various picorna viruses and are used to encode proteins in a single open-reading-frame (ORF). The polyprotein that is produced by the virus is cleaved co-translationally, through a “ribosomal-skipping” mechanism. 2A linked genes have been used in studies to co-express mu...

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Bibliografische gegevens
Hoofdauteur:	Siah, Kok Kian
Andere auteurs:	Yang Yuansheng
Formaat:	Final Year Project (FYP)
Taal:	English
Gepubliceerd in:	2015
Onderwerpen:	DRNTU::Science::Biological sciences
Online toegang:	http://hdl.handle.net/10356/64731

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