The influence of demand satisfication based on customer priorities on clinical trial success rate

In the pharmaceutical industry, introducing a new drug into the market requires billions of dollars in expenditure. Clinical trial costs constitutes of a very expensive development process which includes producing and distributing optimal quantity of inventory. The main priority in clinical trial is...

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Bibliographic Details
Main Author: Palli Menon, Vivek Kakkiyoor
Other Authors: Kan Wu
Format: Final Year Project (FYP)
Language:English
Published: 2015
Subjects:
Online Access:http://hdl.handle.net/10356/64933
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author Palli Menon, Vivek Kakkiyoor
author2 Kan Wu
author_facet Kan Wu
Palli Menon, Vivek Kakkiyoor
author_sort Palli Menon, Vivek Kakkiyoor
collection NTU
description In the pharmaceutical industry, introducing a new drug into the market requires billions of dollars in expenditure. Clinical trial costs constitutes of a very expensive development process which includes producing and distributing optimal quantity of inventory. The main priority in clinical trial is to ensure patients receive appropriate and robust medical supplies swiftly with continuous resupplies. Various studies were performed to determine the right quantity to be produced at the right time using demand forecast information. However, assuming periodic reviews in three phase clinical trials, understanding demand forecast within each period becomes challenging. In this study, a simulation model is created to allocate optimum inventory to satisfy the stochastic demand. This is to minimize the inventory costs using a two-echelon distribution system with rolling scheme. The simulation model is performed using Matlab to determine the customer demand and inventory levels. The simulation study is trying to prove the numerical findings. This is so that the total costs of a two-echelon centralised supply chain decreases monotonically with the initial inventory quantity within a replenishment cycle.
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spelling ntu-10356/649332023-03-04T19:38:39Z The influence of demand satisfication based on customer priorities on clinical trial success rate Palli Menon, Vivek Kakkiyoor Kan Wu School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering In the pharmaceutical industry, introducing a new drug into the market requires billions of dollars in expenditure. Clinical trial costs constitutes of a very expensive development process which includes producing and distributing optimal quantity of inventory. The main priority in clinical trial is to ensure patients receive appropriate and robust medical supplies swiftly with continuous resupplies. Various studies were performed to determine the right quantity to be produced at the right time using demand forecast information. However, assuming periodic reviews in three phase clinical trials, understanding demand forecast within each period becomes challenging. In this study, a simulation model is created to allocate optimum inventory to satisfy the stochastic demand. This is to minimize the inventory costs using a two-echelon distribution system with rolling scheme. The simulation model is performed using Matlab to determine the customer demand and inventory levels. The simulation study is trying to prove the numerical findings. This is so that the total costs of a two-echelon centralised supply chain decreases monotonically with the initial inventory quantity within a replenishment cycle. Bachelor of Engineering (Mechanical Engineering) 2015-06-09T07:17:39Z 2015-06-09T07:17:39Z 2015 2015 Final Year Project (FYP) http://hdl.handle.net/10356/64933 en Nanyang Technological University 46 p. application/pdf
spellingShingle DRNTU::Engineering::Mechanical engineering
Palli Menon, Vivek Kakkiyoor
The influence of demand satisfication based on customer priorities on clinical trial success rate
title The influence of demand satisfication based on customer priorities on clinical trial success rate
title_full The influence of demand satisfication based on customer priorities on clinical trial success rate
title_fullStr The influence of demand satisfication based on customer priorities on clinical trial success rate
title_full_unstemmed The influence of demand satisfication based on customer priorities on clinical trial success rate
title_short The influence of demand satisfication based on customer priorities on clinical trial success rate
title_sort influence of demand satisfication based on customer priorities on clinical trial success rate
topic DRNTU::Engineering::Mechanical engineering
url http://hdl.handle.net/10356/64933
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