Molecular characterization of coronavirus envelope and membrane proteins
Coronaviruses are enveloped viruses with a single strand, positive-sense RNA genome of 27-32 kb in length. In virus-infected cells, a 3’-coterminal nested set of six to nine mRNA species, including the genome-length mRNA (mRNA1) and five to eight subgenomic mRNA species (mRNA2-9), is produced. The f...
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| Format: | Thesis |
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2008
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| Online Access: | https://hdl.handle.net/10356/6568 |
| Summary: | Coronaviruses are enveloped viruses with a single strand, positive-sense RNA genome of 27-32 kb in length. In virus-infected cells, a 3’-coterminal nested set of six to nine mRNA species, including the genome-length mRNA (mRNA1) and five to eight subgenomic mRNA species (mRNA2-9), is produced. The four major structural proteins, spike (S), envelope (E), membrane (M) and nucleocapsid (N), are encoded by different subgenomic mRNAs. |
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