Experimental investigation of a bi-leaflet heart valve

Babies with congenital heart defects require high risk surgeries at birth or adolescence. As the patient matures, replacement of larger artificial valves to accommodate their growth would require additional surgeries. The objective of this experiment is to reduce the amount of re-surgeries required...

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Bibliographic Details
Main Author: Chan, Kah Ming
Other Authors: Yeo Joon Hock
Format: Final Year Project (FYP)
Language:English
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10356/68518
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author Chan, Kah Ming
author2 Yeo Joon Hock
author_facet Yeo Joon Hock
Chan, Kah Ming
author_sort Chan, Kah Ming
collection NTU
description Babies with congenital heart defects require high risk surgeries at birth or adolescence. As the patient matures, replacement of larger artificial valves to accommodate their growth would require additional surgeries. The objective of this experiment is to reduce the amount of re-surgeries required by determining the compatibly of the artificial valves upon the change in diameters of the artery with growth and the method of which the valve was sutured. The valves used are made of expanded polytetrafluoroethylene (ePTFE) with a 13mm diameter kept constant for the various diameters of the silicon conduits ranging from 13mm, 17mm and 21mm. From the experimental results of the 3 different diameters of silicon conduits, the percentage of regurgitation ranged from 7% to 76%.The results showed that the increase in percentage of regurgitation increases linearly with the increase in the diameter of the lumen. Methods used in suturing of the valve affected the regurgitation rate was proven with the experimental results. In comparison to previous experimental results by Jowell Cheng, a correlation found between the 13-21mm silicon conduits yield a 10% variation which can be attributed to different experimental conditions.
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spelling ntu-10356/685182023-03-04T18:26:06Z Experimental investigation of a bi-leaflet heart valve Chan, Kah Ming Yeo Joon Hock School of Mechanical and Aerospace Engineering DRNTU::Engineering Babies with congenital heart defects require high risk surgeries at birth or adolescence. As the patient matures, replacement of larger artificial valves to accommodate their growth would require additional surgeries. The objective of this experiment is to reduce the amount of re-surgeries required by determining the compatibly of the artificial valves upon the change in diameters of the artery with growth and the method of which the valve was sutured. The valves used are made of expanded polytetrafluoroethylene (ePTFE) with a 13mm diameter kept constant for the various diameters of the silicon conduits ranging from 13mm, 17mm and 21mm. From the experimental results of the 3 different diameters of silicon conduits, the percentage of regurgitation ranged from 7% to 76%.The results showed that the increase in percentage of regurgitation increases linearly with the increase in the diameter of the lumen. Methods used in suturing of the valve affected the regurgitation rate was proven with the experimental results. In comparison to previous experimental results by Jowell Cheng, a correlation found between the 13-21mm silicon conduits yield a 10% variation which can be attributed to different experimental conditions. Bachelor of Engineering (Mechanical Engineering) 2016-05-26T07:16:35Z 2016-05-26T07:16:35Z 2016 Final Year Project (FYP) http://hdl.handle.net/10356/68518 en Nanyang Technological University 67 p. application/pdf
spellingShingle DRNTU::Engineering
Chan, Kah Ming
Experimental investigation of a bi-leaflet heart valve
title Experimental investigation of a bi-leaflet heart valve
title_full Experimental investigation of a bi-leaflet heart valve
title_fullStr Experimental investigation of a bi-leaflet heart valve
title_full_unstemmed Experimental investigation of a bi-leaflet heart valve
title_short Experimental investigation of a bi-leaflet heart valve
title_sort experimental investigation of a bi leaflet heart valve
topic DRNTU::Engineering
url http://hdl.handle.net/10356/68518
work_keys_str_mv AT chankahming experimentalinvestigationofabileafletheartvalve